Version 1
: Received: 29 July 2023 / Approved: 31 July 2023 / Online: 1 August 2023 (02:54:51 CEST)
How to cite:
Shojaeian, A.; Barati, N.; Motavallihaghi, S. Investigating the Inhibitory Effects of Hydatid Cyst Fluid and its Antigens on Cancer Progression: A Review. Preprints2023, 2023072141. https://doi.org/10.20944/preprints202307.2141.v1
Shojaeian, A.; Barati, N.; Motavallihaghi, S. Investigating the Inhibitory Effects of Hydatid Cyst Fluid and its Antigens on Cancer Progression: A Review. Preprints 2023, 2023072141. https://doi.org/10.20944/preprints202307.2141.v1
Shojaeian, A.; Barati, N.; Motavallihaghi, S. Investigating the Inhibitory Effects of Hydatid Cyst Fluid and its Antigens on Cancer Progression: A Review. Preprints2023, 2023072141. https://doi.org/10.20944/preprints202307.2141.v1
APA Style
Shojaeian, A., Barati, N., & Motavallihaghi, S. (2023). Investigating the Inhibitory Effects of Hydatid Cyst Fluid and its Antigens on Cancer Progression: A Review. Preprints. https://doi.org/10.20944/preprints202307.2141.v1
Chicago/Turabian Style
Shojaeian, A., Nastaran Barati and Seyedmossa Motavallihaghi. 2023 "Investigating the Inhibitory Effects of Hydatid Cyst Fluid and its Antigens on Cancer Progression: A Review" Preprints. https://doi.org/10.20944/preprints202307.2141.v1
Abstract
Hydatid cyst fluid is a complex biological substance consisting primarily of water, proteins, lipids, carbohydrates, salts, enzymes, hormones, growth factors, immune modulators, and other bioactive molecules. Antigens, including antigen B (AgB) and antigen 5 family members (Ag5), have been identified in hydatid cyst fluid and have been shown to have the ability to inhibit cancer progression. The exact mechanisms by which these components exert inhibitory effects on cancer progression are not fully understood, but it is believed that they may influence multiple signaling pathways involved in cell proliferation, survival, angiogenesis, and metastasis. In vitro studies have demonstrated that treatment with hydatid cyst fluid or specific antigens can inhibit cell growth, induce apoptosis, and suppress the migration of cancer cells. Animal model studies have also demonstrated significant inhibition of tumor growth, reduction in angiogenesis, and suppression of metastasis. Limited clinical studies have shown promising outcomes, including improved overall survival and reduced recurrence rates among breast cancer patients receiving AgB immunotherapy alongside standard treatment.
Keywords
Hydatid cyst fluid; Antigen; Cancer inhibition; Apoptosis; Metastasis
Subject
Medicine and Pharmacology, Oncology and Oncogenics
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
