PreprintReviewVersion 3Preserved in Portico This version is not peer-reviewed
Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.
Version 1
: Received: 24 July 2023 / Approved: 9 August 2023 / Online: 9 August 2023 (12:44:33 CEST)
Version 2
: Received: 13 September 2023 / Approved: 14 September 2023 / Online: 15 September 2023 (11:01:27 CEST)
Version 3
: Received: 4 October 2023 / Approved: 5 October 2023 / Online: 5 October 2023 (14:28:42 CEST)
How to cite:
Nikitiuk, B. E.; Rydzewska-Rosołowska, A.; Kakareko, K.; Głowińska, I.; Hryszko, T. Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.. Preprints2023, 2023071818. https://doi.org/10.20944/preprints202307.1818.v3
Nikitiuk, B. E.; Rydzewska-Rosołowska, A.; Kakareko, K.; Głowińska, I.; Hryszko, T. Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.. Preprints 2023, 2023071818. https://doi.org/10.20944/preprints202307.1818.v3
Nikitiuk, B. E.; Rydzewska-Rosołowska, A.; Kakareko, K.; Głowińska, I.; Hryszko, T. Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.. Preprints2023, 2023071818. https://doi.org/10.20944/preprints202307.1818.v3
APA Style
Nikitiuk, B. E., Rydzewska-Rosołowska, A., Kakareko, K., Głowińska, I., & Hryszko, T. (2023). Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones.. Preprints. https://doi.org/10.20944/preprints202307.1818.v3
Chicago/Turabian Style
Nikitiuk, B. E., Irena Głowińska and Tomasz Hryszko. 2023 "Is modern medicine in need of an overhydration marker in kidney failure? The accuracy of available fluid overload markers and the potential of the new ones." Preprints. https://doi.org/10.20944/preprints202307.1818.v3
Abstract
Overhydration (OH) is a prevalent medical problem occuring in patients with kidney failure, but a specific marker has still not been found. Currently, clinicians employ techniques such as bioimpedance spectroscopy (BIS), ultrasound (US) markers of fluid overload or markers of heart and kidney function such as NT-pro-BNP, GFR or creatinine levels. New serum markers, including but not limited to Ca-125, Galectin-3 (Gal-3), Adrenomedullin (AMD) and Urocortin-2 (UCN-2), are presently under research, displaying promising results. The necessity to ascertain a more precise marker of overhydration is urgent mainly because physical examination is exceptionally imprecise. Signs and symptoms of fluid overload, like edema or gradual increase of body mass, are not always present, notably in patients with chronic kidney disease. This review paper summarizes actual knowledge of a patient's hydration status estimation, focusing specifically on kidney diseases.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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