Foong, D.; Calder, S.; Varghese, C.; Schamberg, G.; Xu, W.; Daker, C.; Ho, V.; Andrews, C.N.; Gharibans, A.A.; O’Grady, G. Gastric Alimetry® Test Interpretation in Gastroduodenal Disorders: Review and Recommendations. J. Clin. Med.2023, 12, 6436.
Foong, D.; Calder, S.; Varghese, C.; Schamberg, G.; Xu, W.; Daker, C.; Ho, V.; Andrews, C.N.; Gharibans, A.A.; O’Grady, G. Gastric Alimetry® Test Interpretation in Gastroduodenal Disorders: Review and Recommendations. J. Clin. Med. 2023, 12, 6436.
Foong, D.; Calder, S.; Varghese, C.; Schamberg, G.; Xu, W.; Daker, C.; Ho, V.; Andrews, C.N.; Gharibans, A.A.; O’Grady, G. Gastric Alimetry® Test Interpretation in Gastroduodenal Disorders: Review and Recommendations. J. Clin. Med.2023, 12, 6436.
Foong, D.; Calder, S.; Varghese, C.; Schamberg, G.; Xu, W.; Daker, C.; Ho, V.; Andrews, C.N.; Gharibans, A.A.; O’Grady, G. Gastric Alimetry® Test Interpretation in Gastroduodenal Disorders: Review and Recommendations. J. Clin. Med. 2023, 12, 6436.
Abstract
Chronic gastroduodenal symptoms are prevalent worldwide, and there is a need for new diagnostic and treatment approaches. Several overlapping processes may contribute to these symptoms, including gastric dysmotility, hypersensitivity, gut-brain axis disorders, gastric outflow resistance, and duodenal inflammation. Gastric Alimetry® (Alimetry, New Zealand) is a non-invasive test for evaluating gastric function that combines body surface gastric mapping (high-resolution electrophysiology) with validated symptom profiling. Together, these complementary data streams enable important new clinical insights into gastric disorders and their symptom correlations, with emerging therapeutic implications. A comprehensive database has been established, currently comprising >2,000 Gastric Alimetry tests, including both controls and patients with various gastroduodenal disorders. From studies employing this database, this pa-per presents a systematic methodology for Gastric Alimetry test interpretation, together with an extensive supporting literature review. Reporting is grouped into four sections: Test Quality, Spectral Analysis, Symptoms, and Conclusions. This review compiles, assesses, and evaluates each of these aspects of test assessment, with discussion of relevant evidence, example cases, limitations, and areas for future work. The resultant interpretation methodology is recommended for use in clinical practice and research to assist clinicians in their use of Gastric Alimetry as a diagnostic aid, and is expected to continue to evolve with further development.
Keywords
Gastroparesis; chronic nausea and vomiting; functional dyspepsia; body surface gastric mapping; disorders of gut brain interaction; motility disorders.
Subject
Medicine and Pharmacology, Gastroenterology and Hepatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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