Version 1
: Received: 25 July 2023 / Approved: 25 July 2023 / Online: 25 July 2023 (09:18:22 CEST)
How to cite:
Vo, N.X.; Che, U.T.T.; Ngo, T.T.T.; Bui, T.T. Economic Evaluation of Glucosamine in Knee Osteoarthritis Treatments in Vietnam. Preprints2023, 2023071678. https://doi.org/10.20944/preprints202307.1678.v1
Vo, N.X.; Che, U.T.T.; Ngo, T.T.T.; Bui, T.T. Economic Evaluation of Glucosamine in Knee Osteoarthritis Treatments in Vietnam. Preprints 2023, 2023071678. https://doi.org/10.20944/preprints202307.1678.v1
Vo, N.X.; Che, U.T.T.; Ngo, T.T.T.; Bui, T.T. Economic Evaluation of Glucosamine in Knee Osteoarthritis Treatments in Vietnam. Preprints2023, 2023071678. https://doi.org/10.20944/preprints202307.1678.v1
APA Style
Vo, N.X., Che, U.T.T., Ngo, T.T.T., & Bui, T.T. (2023). Economic Evaluation of Glucosamine in Knee Osteoarthritis Treatments in Vietnam. Preprints. https://doi.org/10.20944/preprints202307.1678.v1
Chicago/Turabian Style
Vo, N.X., Thanh Thi Thanh Ngo and Tien Thuy Bui. 2023 "Economic Evaluation of Glucosamine in Knee Osteoarthritis Treatments in Vietnam" Preprints. https://doi.org/10.20944/preprints202307.1678.v1
Abstract
Osteoarthritis (OA) is the degeneration of cartilage in joints that results in bones rubbing against each other, it causes uncomfortable symptoms such as pain, swelling, stiffness, and can lead to disability. It usually occurs in the elderly and causes a large medical burden. The aim of this study is to evaluate cost-effectiveness between the standard treatment for osteoarthritis and the standard treatment with added crystalline glucosamine sulfate at various stages. The Markov analysis modelling was applied to evaluate the effect of both adding glucosamine compared to standard treatment from a societal perspective during whole patients’ lifetimes. Data input was collected by review in previous studies. The outcome was measured in quality-adjusted life years (QALYs), and the incremental cost-effectiveness ratio (ICER) from a societal perspective was ap-plied with 3%-discounted for all cost and outcome. One-way analysis via Tornado diagram was performed to investigate the change of factors in model. In general, the adding glucosamine into the standard treatment proved to be more cost-effectiveness compared to the standard treatment. Particularly, early stage adding glucosamine in the treatment was cost-effectiveness then post-stage adding glucosamine. The addition of supplementing crystalline glucosamine sulfate to whole regimen at any stage was cost-effectiveness at willingness-to-pay (WTP) threshold
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
