Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Misconceptions and Knowledge Gaps on Antibiotic Use in Primary Care – a Delphi Study in Four Sectors and Five European Countries

Version 1 : Received: 14 July 2023 / Approved: 18 July 2023 / Online: 18 July 2023 (12:23:26 CEST)

A peer-reviewed article of this Preprint also exists.

Chalkidou, A.; Lambert, M.; Cordoba, G.; Taxis, K.; Hansen, M.P.; Bjerrum, L. Misconceptions and Knowledge Gaps on Antibiotic Use and Resistance in Four Healthcare Settings and Five European Countries—A Modified Delphi Study. Antibiotics 2023, 12, 1435. Chalkidou, A.; Lambert, M.; Cordoba, G.; Taxis, K.; Hansen, M.P.; Bjerrum, L. Misconceptions and Knowledge Gaps on Antibiotic Use and Resistance in Four Healthcare Settings and Five European Countries—A Modified Delphi Study. Antibiotics 2023, 12, 1435.

Abstract

Background: Misconceptions and knowledge gaps about antibiotic use contribute to inappropriate antibiotic use and antimicrobial resistance. Aim: Identifying and prioritizing misconceptions and knowledge gaps about antibiotic use from a healthcare professionals’ perspective. Methods: A modified Delphi study of two rounds with an expert meeting. A literature search was conducted to create statements about misconceptions and knowledge gaps about antibiotic use. These were rated by healthcare professionals from five EU countries representing general practice, out-of-hour services, nursing homes, and pharmacies. Consensus was achieved if ≥80% of the participants rated 4+ on a five-point Likert scale during the second Delphi round. Results. In total, 44 misconceptions were identified through the literature search within four themes: 1) antimicrobial resistance in general, 2) use of antibiotics in general, 3) use of antibiotics for respiratory tract infections, and 4) use of antibiotics for urinary tract infections. Consensus was reached for more than half of the statements within each setting. Conclusions. Experts from different settings and nationalities acknowledge that multiple misconceptions and knowledge gaps can contribute to inappropriate use of antibiotics in the community. These results provide valuable information to use in educational campaigns for patients and healthcare professionals to improve the use of antibiotics.

Keywords

antimicrobial resistance; antibiotics; antibiotic use; misconceptions and knowledge gaps; general practice; out-of-hours services; nursing homes; community pharmacies

Subject

Public Health and Healthcare, Primary Health Care

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