Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Comparison of Corvis ST Parameters between Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma

Yuta Nakaniida
* ORCID logo ,
Kana Tokumo
,
Hiromitsu Onoe
ORCID logo ,
Naoki Okada
ORCID logo ,
Shunsuke Nakakura
,
Ryo Asaoka
,
Yoshiaki Kiuchi
ORCID logo
Version 1 : Received: 13 July 2023 / Approved: 14 July 2023 / Online: 14 July 2023 (15:21:50 CEST)

A peer-reviewed article of this Preprint also exists.

Nakaniida, Y.; Tokumo, K.; Onoe, H.; Okada, N.; Nakakura, S.; Asaoka, R.; Kiuchi, Y. Comparison of Corvis ST Parameters between Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma. J. Clin. Med. 2023, 12, 5108. Nakaniida, Y.; Tokumo, K.; Onoe, H.; Okada, N.; Nakakura, S.; Asaoka, R.; Kiuchi, Y. Comparison of Corvis ST Parameters between Primary Open-Angle Glaucoma and Primary Angle-Closure Glaucoma. J. Clin. Med. 2023, 12, 5108.

Abstract

Background: We compared corneal visualization Scheimpflug technology (CST) parameters between eyes with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). Methods: A retrospective analysis was done on data from 89 eyes with POAG and 83 eyes with PACG that had CST examinations. CST parameters were compared between eyes with POAG and those with PACG using a linear mixed model (LMM). Results: No differences were observed in age, central corneal thickness, intraocular pressure, or use of antiglaucoma eye drops between the two groups. Patients with PACG had a significantly shorter axial length (AL), a higher proportion of females, CST parameters, longer applanation 2 (A2) time, deeper A2 deformation amplitude, shorter peak distance (PD), longer whole eye movement, and longer whole eye movement time than patients with POAG. Highest concavity (HC) length and PD showed a significant positive correlation with AL. However, A1 length, A1 deformation amplitude, A2 time, A2 velocity, A2 length, A2 deformation amplitude, HC time, whole eye movement, and whole eye movement time were negatively correlated with AL. Conclusions: Biomechanical properties of the cornea differed between PACG and POAG. In some parts, AL differences between the POAG and PACG groups might contribute to the variation in CST parameters.

Keywords

Corvis ST; POAG; PACG; glaucoma; cornea

Subject

Medicine and Pharmacology, Ophthalmology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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