Version 1
: Received: 13 July 2023 / Approved: 14 July 2023 / Online: 14 July 2023 (08:49:28 CEST)
How to cite:
Tutunaru, C. V.; Ică, O. M.; Mitroi, G. F.; Neagoe, C. D.; Mitroi, G. G.; Ianosi, S. L. Hereditary Angioedema. Preprints2023, 2023070996. https://doi.org/10.20944/preprints202307.0996.v1
Tutunaru, C. V.; Ică, O. M.; Mitroi, G. F.; Neagoe, C. D.; Mitroi, G. G.; Ianosi, S. L. Hereditary Angioedema. Preprints 2023, 2023070996. https://doi.org/10.20944/preprints202307.0996.v1
Tutunaru, C. V.; Ică, O. M.; Mitroi, G. F.; Neagoe, C. D.; Mitroi, G. G.; Ianosi, S. L. Hereditary Angioedema. Preprints2023, 2023070996. https://doi.org/10.20944/preprints202307.0996.v1
APA Style
Tutunaru, C. V., Ică, O. M., Mitroi, G. F., Neagoe, C. D., Mitroi, G. G., & Ianosi, S. L. (2023). Hereditary Angioedema. Preprints. https://doi.org/10.20944/preprints202307.0996.v1
Chicago/Turabian Style
Tutunaru, C. V., George G. Mitroi and Simona Laura Ianosi. 2023 "Hereditary Angioedema" Preprints. https://doi.org/10.20944/preprints202307.0996.v1
Abstract
Hereditary angioedema (HAE) is a very rare and potentially life-threatening genetic disease characterized by low levels of C1-INH inhibitor esterase and involving recurrent attacks of non-pruritic angioedema that do not leave subcutaneous or mucosal wells without the presence of hives. It occurs worldwide in 1 in 50,000 to 150,000 individuals and accounts for approximately 2% of clinical angioedema. It affects both sexes equally and can affect all races without ethnic differences. Methods: We conducted a review in Pubmed regarding this disease using keywords such as: hereditary angioedema, guideline, treatment, prophylaxis, management. Results: We analysed 195 articles and we focused our study on 17 reviews about type I of HAE published in English in the last 10 years. Conclusions: Screening among the family members of affected individuals (even if symptoms are absent) is mandatory, since it is a life-threatening condition. Moreover, advances in diagnosis and management have significantly improved the outcomes and quality of life of patients with hereditary angioedema.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
