Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Risk Factors of Health-Related Quality of Life Among Gastrointestinal Cancer Survivors in the U.S: With a Focus on Social and Behavioral Determinants of Health (SBDH)

Version 1 : Received: 5 July 2023 / Approved: 6 July 2023 / Online: 6 July 2023 (12:31:10 CEST)

A peer-reviewed article of this Preprint also exists.

Han, C.J.; Tounkara, F.; Kalady, M.; Noonan, A.M.; Burse, N.R.; Paskett, E.D.; Von Ah, D. Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH). Int. J. Environ. Res. Public Health 2023, 20, 6676. Han, C.J.; Tounkara, F.; Kalady, M.; Noonan, A.M.; Burse, N.R.; Paskett, E.D.; Von Ah, D. Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH). Int. J. Environ. Res. Public Health 2023, 20, 6676.

Abstract

Background: Increasing number of long-term gastrointestinal (GI) cancer survivors highlights the importance of understanding factors that contribute to their health-related quality of life (HRQoL). We investigated the risk factors of HRQoL, in-cluding demographics, clinical characteristics, and social and behavioral determinants of health (SBDH). Methods: Adult GI cancer survivors (n = 3,201) in the BRFSS surveys from 2014-2021 (except for 2015) were analyzed. Unadjusted/adjusted logistic regression was used. Results: The majority were female (54%) and White (78%), with a median age of 67. Survivors who were 65 years or older, diagnosed with colorectal cancer, or who had fewer comorbidities were more likely to report significantly better HRQoL. Significant social factors of poor HRQoL were being unmarried, racial and ethnic minorities, low socioeconomic status, and poor health care access. Significant behavioral factors of poor HRQoL were lack of physical activity, heavy alcohol consumption, and current smoking, with lack of physical activity being the most significant factor. Conclusions: The SBDH have a critical role in HRQoL. Future studies are warranted to develop a tailored survivorship intervention, such as physical rehabilitation and to ex-plore machine learning/artificial intelligence predictive models to identify cancer sur-vivors at a high risk of developing poor HRQoL.

Keywords

Gastrointestinal; Cancer survivor; Social and behavioral determinants of health; Health-related quality of life

Subject

Public Health and Healthcare, Primary Health Care

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.