Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Recombinant Laccase: A Promising Tool for Industrial Effluent Bioremediation

Vishal Chandra
,
Kumari Arpita
,
Pramod Yadav
* ORCID logo ,
Viaks Raghuvanshi
,
Amarjeet Yadav
,
Samim Ali
,
Vivek Mani Tripathi
,
Sandeep Prajapati
Version 1 : Received: 30 June 2023 / Approved: 3 July 2023 / Online: 3 July 2023 (10:00:02 CEST)

A peer-reviewed article of this Preprint also exists.

Yadav, P., Chandra, V., Arpita, K., Raghuvanshi, V., Yadav, A., et al. (2023). Recombinant Laccase: A Promising Tool for Industrial Effluent Bioremediation. Journal of Earth & Environmental Waste Management, 1(1), 1-6. Yadav, P., Chandra, V., Arpita, K., Raghuvanshi, V., Yadav, A., et al. (2023). Recombinant Laccase: A Promising Tool for Industrial Effluent Bioremediation. Journal of Earth & Environmental Waste Management, 1(1), 1-6.

Abstract

Industrial effluents contain contaminants that pose threats to the environment and human health. Bioremediation is an environmentally friendly, sustainable, and cost-effective approach to degrade or transform pollutants using microbial enzymes. Laccase is a versatile enzyme that oxidizes a wide range of substrates, such as dyes, phenolic compounds, pesticides, and polycyclic aromatic hydrocarbons (PAHs), with the consumption of molecular oxygen. Laccase can also remove heavy metals by forming complexes with organic ligands or reducing them to fewer toxic forms. However, the application of laccase in bioremediation is limited by its low production, stability, and specificity. Recombinant technology has been employed to enhance the expression, activity, and stability of laccase in various bacterial hosts. Immobilization techniques have been developed to improve the reusability and stability of laccase in different environmental conditions. This review summarizes the recent developments in the production optimization of recombinant laccase enzymes and their role in the bioremediation of industrial effluents. It also discusses the challenges of laccase-based biocatalytic systems for environmental cleanup.

Keywords

Environmental pollution; Sustainable development; Cost-effectiveness; Enzyme technology; Recombinant technology

Subject

Environmental and Earth Sciences, Environmental Science

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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