Review
Version 1
Preserved in Portico This version is not peer-reviewed
Carbohydrate-containing Low Molecular Weight Metabolites of Microalgae
Version 1
: Received: 28 June 2023 / Approved: 28 June 2023 / Online: 28 June 2023 (12:02:33 CEST)
A peer-reviewed article of this Preprint also exists.
Stonik, V.A.; Stonik, I.V. Carbohydrate-Containing Low Molecular Weight Metabolites of Microalgae. Mar. Drugs 2023, 21, 427. Stonik, V.A.; Stonik, I.V. Carbohydrate-Containing Low Molecular Weight Metabolites of Microalgae. Mar. Drugs 2023, 21, 427.
Abstract
Microalgae are abundant components of biosphere rich in low molecular weight carbohy-drate-containing natural products (glycoconjugates). Glycoconjugates take a part in processes of photosynthesis, provide producers with important biological properties, influence other organ-isms and known by biological activities. Some of them, for example glycosylated toxins and ar-senicals, are detrimental and can be transferring via food chains into higher organisms including humans. So far, the studies on a series of particular groups of microalgal glycoconjugates were not comprehensively discussed in special reviews. In this review, a special focus was made on the isolation, structure determination, properties and approaches to the search for new bioactive metabolites. Analysis of literature data concerning structures, functions and biological activities of ribosylated arsenicals, galactosylated and sulfoquinovosylated lipids, phosphoglycolipids, gly-coside derivatives of toxins, and other groups of glycoconjugates was carried out and discussed. The discovery of a great variety of new carbohydrate-containing metabolites, important biological roles some of them, participation in regulation of microalgal blooms via viral infections as well as the detection of potent immunomodulatory activity, shown by these type metabolites could be attributed to the most interesting recent achievements. Structures, properties and biological roles of glycoconjugates from microalgae attract a great attention growing year to year.
Keywords
microalgae; glycoconjugates; arsenicals; galactolipids; sulfoquinovosyl-containing glycolipids; phosphoglycolipids; steryl glycosides; glycosylated long chain polyketides; regulation of mi-croalgal blooms; dietary constituents.
Subject
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments (0)
We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.
Leave a public commentSend a private comment to the author(s)
* All users must log in before leaving a comment
