Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Stability as Predictor of Mortality in Low-Energy Spinal Fractures: A Retrospective Analysis of 1356 Cases

Version 1 : Received: 15 June 2023 / Approved: 16 June 2023 / Online: 16 June 2023 (10:31:00 CEST)

How to cite: Juhász, Á.; Süvegh, D.; Veres, D.S.; Viola, Á. Stability as Predictor of Mortality in Low-Energy Spinal Fractures: A Retrospective Analysis of 1356 Cases. Preprints 2023, 2023061219. https://doi.org/10.20944/preprints202306.1219.v1 Juhász, Á.; Süvegh, D.; Veres, D.S.; Viola, Á. Stability as Predictor of Mortality in Low-Energy Spinal Fractures: A Retrospective Analysis of 1356 Cases. Preprints 2023, 2023061219. https://doi.org/10.20944/preprints202306.1219.v1

Abstract

Osteoporotic spinal fractures represent an increasingly widespread health problem in our aging society. We aimed to investigate the treatment options for low-energy spinal fractures in the el-derly and their impact on mortality, focusing on surgical stabilization using minimally invasive and open techniques. We evaluated 1356 patients over 50 years of age with compression frac-tures sustained due to low energy trauma treated at a single trauma center. We compared the mortality of patients following stable and operated/non-operated unstable compression frac-tures and the eligibility to surgery using the open and minimally invasive approach. The pa-tients received surgical or conservative care according to severity and eligibility to surgery. The mortality hazard ratio of patients who underwent screw fixation was 1.02 (P > .91), of patients who refused surgery was 1.68 (P < .001) and that of patients with anesthesiological contraindica-tion was 1.57 (P = .08), compared to conservatively treated patients with stable fractures. The dif-ference in mortality between open and minimally invasive surgeries was not significant, but the number of patients eligible for surgery with the minimally invasive procedure was significantly higher (OR: 0.25; P < .001). Spinal stability after fractures may be an important predictor of sur-vival in patients with low-impact fractures.

Keywords

osteoporosis; osteoporotic spine fracture; spine stability; minimally invasive spine surgery; survival analysis; unstable spine fracture; low-impact compression fracture; fragility fracture

Subject

Medicine and Pharmacology, Surgery

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