Kumar, A.; Patra, P.; Nutan, B.; Bhalani, D.V.; Chandel, A.K.S. Polymeric Hydrogels As Drug Delivery Vehicles. Preprints2023, 2023061118. https://doi.org/10.20944/preprints202306.1118.v1
APA Style
Kumar, A., Patra, P., Nutan, B., Bhalani, D.V., & Chandel, A.K.S. (2023). Polymeric Hydrogels As Drug Delivery Vehicles. Preprints. https://doi.org/10.20944/preprints202306.1118.v1
Chicago/Turabian Style
Kumar, A., Dixit V Bhalani and Arvind Kuamr Singh Chandel. 2023 "Polymeric Hydrogels As Drug Delivery Vehicles" Preprints. https://doi.org/10.20944/preprints202306.1118.v1
Abstract
Polymeric hydrogels are promising polymeric functional materials that have been widely used in the biomedical field as an emerging carrier of various therapeutic agents. Polymeric hydrogels as a carrier of therapeutics can leverage therapeutically beneficial outcomes of drug delivery than systemic chemotherapy and can provide spatial and temporal control over the release of various therapeutic agents. Polymeric hydrogels are cross-linked three-dimensional networks constructed by hydrophilic polymers and they are capable of absorbing and re-taining a large amount of water. Polymeric hydrogels share many physiochemical features with natural tissues due to their water abundance, biomimetic microstructure, and intrinsic flexibility. Polymeric hydrogels have excellent biocompatibility, biodegradability, and lower toxicity. Polymeric hydrogels enhance the convenience and efficiency of drug delivery by assisting in situ gelation and controlling drug release by changing their volume and other properties when it encounters some stimuli (e.g., heat, pH, light, and ultrasound). This review aims to outline the overview of polymeric hydrogels, properties, types, advantage, disadvantages, characteri-zation, and their application with present status and future perspective used for the delivery of therapeutics in pharmaceutical and biomedical sciences.
Keywords
Cancer; Drug delivery systems; Polymeric hydrogels; Stimuli-responsive materials
Subject
Chemistry and Materials Science, Biomaterials
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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