Version 1
: Received: 14 June 2023 / Approved: 14 June 2023 / Online: 14 June 2023 (08:31:55 CEST)
How to cite:
Lopez-Jornet, P.; Olmo-Monedero, A.; P Rubio, C.; Pons-Fuster, E.; Tvarijonaviciute, A. Study of Adenosine Deaminase, Ferritin and Total Proteins as Salivary Biomarkers in Patients with Oral Potentially Malignant Disorders (OPMD). Preprints2023, 2023061015. https://doi.org/10.20944/preprints202306.1015.v1
Lopez-Jornet, P.; Olmo-Monedero, A.; P Rubio, C.; Pons-Fuster, E.; Tvarijonaviciute, A. Study of Adenosine Deaminase, Ferritin and Total Proteins as Salivary Biomarkers in Patients with Oral Potentially Malignant Disorders (OPMD). Preprints 2023, 2023061015. https://doi.org/10.20944/preprints202306.1015.v1
Lopez-Jornet, P.; Olmo-Monedero, A.; P Rubio, C.; Pons-Fuster, E.; Tvarijonaviciute, A. Study of Adenosine Deaminase, Ferritin and Total Proteins as Salivary Biomarkers in Patients with Oral Potentially Malignant Disorders (OPMD). Preprints2023, 2023061015. https://doi.org/10.20944/preprints202306.1015.v1
APA Style
Lopez-Jornet, P., Olmo-Monedero, A., P Rubio, C., Pons-Fuster, E., & Tvarijonaviciute, A. (2023). Study of Adenosine Deaminase, Ferritin and Total Proteins as Salivary Biomarkers in Patients with Oral Potentially Malignant Disorders (OPMD). Preprints. https://doi.org/10.20944/preprints202306.1015.v1
Chicago/Turabian Style
Lopez-Jornet, P., Eduardo Pons-Fuster and Asta Tvarijonaviciute. 2023 "Study of Adenosine Deaminase, Ferritin and Total Proteins as Salivary Biomarkers in Patients with Oral Potentially Malignant Disorders (OPMD)" Preprints. https://doi.org/10.20944/preprints202306.1015.v1
Abstract
Objective: A study was made of the salivary levels of adenosine deaminase (ADA), ferritin (FRR) and total proteins in healthy individuals and in patients with oral potentially malignant disorders (OPMD), assessing the potential role of saliva as a diagnostic tool.
Methods: A total of 91 subjects participated in the study, divided into two groups: 59 patients with OPMD (oral leukoplakia or oral lichen planus )and 32 healthy controls with measurements being made of salivary ADA, ferritin (FRR) and total proteins (TP).
Results: There were no significant differences in salivary ADA between the OPMD group and the controls (p=0.934), though the levels of both FRR and TP were significantly higher in the OPMD group (p=0.001). Patients with oral lichen planus showed significant differences in terms of FRR (p=0.009) and TP (p=0.003).
Conclusions: The promising findings of this study suggest a potential role for FRR and TP in the salivary diagnosis of OPMD. In addition, saliva appears to be a reliable tool offering an interesting alternative for the screening of large populations.
Medicine and Pharmacology, Dentistry and Oral Surgery
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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