Version 1
: Received: 7 June 2023 / Approved: 8 June 2023 / Online: 8 June 2023 (10:45:43 CEST)
How to cite:
Sebastiani, F.; D'Alterio, C.; Vocca, C.; Gallelli, L.; Palumbo, F.; Cai, T.; Palmieri, A. Effectiveness of Silymarin, Sulforaphane, Lycopene, Green Tea, Tryptophan, Glutathione and Escin on Human Health: Results of a Narrative Review. Preprints2023, 2023060631. https://doi.org/10.20944/preprints202306.0631.v1
Sebastiani, F.; D'Alterio, C.; Vocca, C.; Gallelli, L.; Palumbo, F.; Cai, T.; Palmieri, A. Effectiveness of Silymarin, Sulforaphane, Lycopene, Green Tea, Tryptophan, Glutathione and Escin on Human Health: Results of a Narrative Review. Preprints 2023, 2023060631. https://doi.org/10.20944/preprints202306.0631.v1
Sebastiani, F.; D'Alterio, C.; Vocca, C.; Gallelli, L.; Palumbo, F.; Cai, T.; Palmieri, A. Effectiveness of Silymarin, Sulforaphane, Lycopene, Green Tea, Tryptophan, Glutathione and Escin on Human Health: Results of a Narrative Review. Preprints2023, 2023060631. https://doi.org/10.20944/preprints202306.0631.v1
APA Style
Sebastiani, F., D'Alterio, C., Vocca, C., Gallelli, L., Palumbo, F., Cai, T., & Palmieri, A. (2023). Effectiveness of Silymarin, Sulforaphane, Lycopene, Green Tea, Tryptophan, Glutathione and Escin on Human Health: Results of a Narrative Review. Preprints. https://doi.org/10.20944/preprints202306.0631.v1
Chicago/Turabian Style
Sebastiani, F., Tommaso Cai and Alessandro Palmieri. 2023 "Effectiveness of Silymarin, Sulforaphane, Lycopene, Green Tea, Tryptophan, Glutathione and Escin on Human Health: Results of a Narrative Review" Preprints. https://doi.org/10.20944/preprints202306.0631.v1
Abstract
Background: Recently the role of nutraceutical compounds in the prevention of human diseases is rapidly increasing. Here, we aim to evaluate the beneficial effect of dietary supplementation with seven active principles, lycopene, sulphoraphane, silymarin, glutathione, escin, tryptophan, green tea catechins, on human health. Methods: An extensive search of PubMed and Medline database was performed with the following keywords: “silymarin”, “sulforaphane”, “lycopene”, “green tea catechins”, “tryptophan”, “glutathione” and “escin” accompanied by the keywords “supplement”, “supplementation”, “nutraceutics”. All pre-clinical and clinical trials have been considered for this review. Results: One-hundred and eighteen full-text articles were eligible for inclusion in this review. The papers examined presented considerable variability due to the wide heterogeneity of dosages administered, population involved and outcomes pursued. Conclusion: Nutritional supplementation with lycopene, sulphoraphane, silymarin, glutathione, escin, tryptophan and green tea catechins appears to exert a wide range of benefits on human health, ranging from mood and cognition to cardiovascular health, fertility, metabolism, antioxidant and anti-inflammatory capabilities, potential anti-cancer effects. Further studies are required to better define the potential synergic effect, optimal dosage, mechanism of action and tolerability profile of these substances.
Keywords
sulphoraphane; silymarin; lycopene; glutathione; escin; tryptophan; green tea; men health; prevention
Subject
Public Health and Healthcare, Public Health and Health Services
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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