Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Bias in Youth with Functional Abdominal Pain (BY-FAP) – A new experimental design to examine cognitive biases for gastrointestinal related stimuli in children and adolescents

Version 1 : Received: 30 May 2023 / Approved: 1 June 2023 / Online: 1 June 2023 (04:16:01 CEST)

A peer-reviewed article of this Preprint also exists.

Bjerre-Nielsen, E.; Kallesøe, K.H.; Nielsen, E.S.; Gehrt, T.B.; Frostholm, L.; Rask, C.U. A New Experimental Design to Examine Cognitive Biases for Gastrointestinal Related Stimuli in Children and Adolescents. Children 2023, 10, 1327. Bjerre-Nielsen, E.; Kallesøe, K.H.; Nielsen, E.S.; Gehrt, T.B.; Frostholm, L.; Rask, C.U. A New Experimental Design to Examine Cognitive Biases for Gastrointestinal Related Stimuli in Children and Adolescents. Children 2023, 10, 1327.

Abstract

Cognitive biases towards disorder-specific stimuli are suggested to be crucial in the development and maintenance of symptoms in adults with functional gastrointestinal disorders (FGID). Functional abdominal pain disorders (FAPD), a subtype of FGID, are common in children and adolescents, but the influence of cognitive biases is sparsely examined. The aim of this study was to 1) develop a new experimental design for assessing cognitive biases towards gastrointestinal stimuli in children and adolescents (age 8-17 years) and 2) test its feasibility on a healthy sample exploring potential sex- and age-related differences. The online experimental design – BY-FAP (Bias in Youth with Functional Abdominal Pain) includes a word task and a picture task. Stimuli in both tasks are related to general and gastrointestinal symptoms and the design includes three phases: 1) encoding, 2) free recall and 3) recognition. Results from 96 healthy participants (Mage = 12.3, 47.9% female) found no significant difference between sex or age groups in recall and recognition of either words or pictures. The results support that the design is feasible for children and adolescents. In the future, BY-FAP can be used to explore possible cognitive biases in children and adolescents with FAPD.

Keywords

Adolescent; children; cognitive bias; functional abdominal pain disorder; functional gastrointestinal disorders; interpretation bias; memory bias

Subject

Medicine and Pharmacology, Psychiatry and Mental Health

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