Review
Version 1
Preserved in Portico This version is not peer-reviewed
Biosensing for Autoimmune Chronic Disease: A Review
Version 1
: Received: 29 May 2023 / Approved: 30 May 2023 / Online: 30 May 2023 (08:25:35 CEST)
A peer-reviewed article of this Preprint also exists.
Golfinopoulou, R.; Kintzios, S. Biosensing for Autoimmune Chronic Disease—A Review. Chemosensors 2023, 11, 366. Golfinopoulou, R.; Kintzios, S. Biosensing for Autoimmune Chronic Disease—A Review. Chemosensors 2023, 11, 366.
Abstract
Although relatively rare, affecting 8% of the general population, autoimmune disorders are causative linked with chronic diseases and morbidity. Control of the course of the disease is closely dependent on the ability to monitor its onset as well as response to treatment. In the present report, we review the progress in the development of biosensor-based approaches and related tools for the Point-of-Care diagnosis and monitoring of biomarkers related to several autoimmune diseases, such as Myasthenia Gravis, Rheumatoid Arthritis, Multiple Sclerosis, Systemic Erythematosus Lupus, Crohn’s Disease, Diabetes Mellitus, Behcet’s disease, Psoriasis and Celiac Disease. Various biosensing technologies are discussed, including electrochemical, optical and mechanical ones, along with the use of advanced nanomaterials and immobilization techniques for the biorecognition elements. The need for innovative devices with unique features of rapid, low-cost, real-time detection is considered in the context of preventing permanent organ and tissue damage from chronic autoimmune diseases.
Keywords
autoantibodies; autoimmune; biomarker; biosensor; chronic disease; cytokines; microRNAs; Point-of-Care
Subject
Biology and Life Sciences, Biology and Biotechnology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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