Arcadi, A.; Morlacci, V.; Palombi, L. Synthesis of Nitrogen-Containing Heterocyclic Scaffolds through Sequential Reactions of Aminoalkynes with Carbonyls. Molecules2023, 28, 4725.
Arcadi, A.; Morlacci, V.; Palombi, L. Synthesis of Nitrogen-Containing Heterocyclic Scaffolds through Sequential Reactions of Aminoalkynes with Carbonyls. Molecules 2023, 28, 4725.
Arcadi, A.; Morlacci, V.; Palombi, L. Synthesis of Nitrogen-Containing Heterocyclic Scaffolds through Sequential Reactions of Aminoalkynes with Carbonyls. Molecules2023, 28, 4725.
Arcadi, A.; Morlacci, V.; Palombi, L. Synthesis of Nitrogen-Containing Heterocyclic Scaffolds through Sequential Reactions of Aminoalkynes with Carbonyls. Molecules 2023, 28, 4725.
Abstract
Sequential reactions of aminoalkynes represent a powerful tool to easily assembly biologically important polyfunctionalized nitrogen heterocyclic scaffolds. Metal catalysis often plays a key role in terms of selectivity, efficiency, atom economy and green chemistry of these sequential approaches. This review examines the existing literature on the applications of reactions of aminoalkynes with carbonyls which are emerging for their synthetic potential. Aspect concerning the features of the starting reagents, the catalytic systems, alternative reaction conditions and the pathways as well as the possible intermediates are provided.
Keywords
Sequential Reactions; Aminolkynes; Heterocycles; Metal catalysis.
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright:
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