Review
Version 1
Preserved in Portico This version is not peer-reviewed
Peripapillary Intrachoroidal Cavitation
Version 1
: Received: 11 May 2023 / Approved: 12 May 2023 / Online: 12 May 2023 (09:00:13 CEST)
A peer-reviewed article of this Preprint also exists.
Ehongo, A.; Bacq, N. Peripapillary Intrachoroidal Cavitation. J. Clin. Med. 2023, 12, 4712. Ehongo, A.; Bacq, N. Peripapillary Intrachoroidal Cavitation. J. Clin. Med. 2023, 12, 4712.
Abstract
Peripapillary intrachoroidal cavitation (PICC) is a yellow-orange lesion, located at the outer border of the myopic conus. First described as a localized detachment of the retinal pigment epithelium, its intrachoroidal location was later disclosed, justifying its current name. PICC is related to other myopic complications like posterior staphyloma, but its pathogenesis is not clear to date. Although it has been considered a benign condition, most eyes with PICC show visual field defects, leading to diagnostic uncertainty as these deficits resemble those observed in glaucoma. Furthermore, eyes with PICC can develop macular detachment with retinoschisis. Finally, misdiagnosis of PICC as a metastatic choroidal tumor may lead to unnecessary and anxiety-provoking investigation. Advances in optical coherence tomography (OCT) imaging have improved the visualization of ocular structures, contributing to the understanding of PICC. Recently high optic nerve sheaths traction forces during eye movements in highly myopic eyes have been suggested as promoters of PICC, renewing interest around this condition. However, a review of PICC is still lacking. Therefore, we aimed to provide a concise yet comprehensive overview of the current state of the art, focusing on OCT documentation, pathophysiology and potential future perspectives based on biomechanics of the optic nerve.
Keywords
Myopia; peripapillary intrachoroidal cavitation; Peripapillary staphyloma; gamma peripapillary atrophy; border tissue; optic nerve sheaths; biomechanics
Subject
Medicine and Pharmacology, Clinical Medicine
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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