Pathology Outlines of Post-COVID-19 Pulmonary Fibrosis Comparative with Idiopathic Pulmonary Fibrosis

Roxana-Elena Cîrjaliu; Mariana Deacu; Ioana Gherghișan; Angela-Ștefania Marghescu; Manuela Enciu; Gabriela-Izabela Băltățescu; Antonela Anca Nicolau; Doina-Ecaterina Tofolean; Oana Cristina Arghir; Ariadna Petronela Fildan

doi:10.20944/preprints202305.0181.v1

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preprints.org > medicine and pharmacology > pulmonary and respiratory medicine > doi: 10.20944/preprints202305.0181.v1

Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Pathology Outlines of Post-COVID-19 Pulmonary Fibrosis Comparative with Idiopathic Pulmonary Fibrosis

Roxana-Elena Cîrjaliu

Mariana Deacu

^* ,

Ioana Gherghișan

^* ,

Angela-Ștefania Marghescu

Manuela Enciu

Gabriela-Izabela Băltățescu

Antonela Anca Nicolau

Doina-Ecaterina Tofolean

Oana Cristina Arghir

Ariadna Petronela Fildan

Version 1 : Received: 28 April 2023 / Approved: 4 May 2023 / Online: 4 May 2023 (04:09:04 CEST)

A peer-reviewed article of this Preprint also exists.

Cîrjaliu, R.-E.; Deacu, M.; Gherghișan, I.; Marghescu, A.-Ș.; Enciu, M.; Băltățescu, G.I.; Nicolau, A.A.; Tofolean, D.-E.; Arghir, O.C.; Fildan, A.-P. Clinicopathological Outlines of Post-COVID-19 Pulmonary Fibrosis Compared with Idiopathic Pulmonary Fibrosis. Biomedicines 2023, 11, 1739. Cîrjaliu, R.-E.; Deacu, M.; Gherghișan, I.; Marghescu, A.-Ș.; Enciu, M.; Băltățescu, G.I.; Nicolau, A.A.; Tofolean, D.-E.; Arghir, O.C.; Fildan, A.-P. Clinicopathological Outlines of Post-COVID-19 Pulmonary Fibrosis Compared with Idiopathic Pulmonary Fibrosis. Biomedicines 2023, 11, 1739.

Abstract

This review brings together the current knowledge regarding the risk factors, and the clinical, radiologic and histological features of both post-COVID-19 interstitial pul-monary fibrosis (PCPF) and Idiopathic Pulmonary Fibrosis (IPF) with a particular fo-cus on describing the similarities and the disparities between the fibrotic changes in these two diseases. It is important to highlight the common points of PCPF and IPF to observe if they are some targetable changes to improve patient outcomes. The litera-ture review was performed using numerous databases to identify relevant articles published in English through October 2022. This review would help clinicians, pathologists and researchers to make an accurate diagnosis, which can be useful in identifying the group of patients who can be selected for antifibrotic therapies, and future therapeutic perspectives.

Keywords

Covid-19; idiopathic pulmonary fibrosis; interstitial lung disease; pulmonary fibrosis

Subject

Medicine and Pharmacology, Pulmonary and Respiratory Medicine

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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