Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Bioengineering Microbes for Improved Nutritional Value and Health Benefits.

Version 1 : Received: 1 May 2023 / Approved: 2 May 2023 / Online: 2 May 2023 (05:04:55 CEST)

How to cite: Pandya, J.; Adiga, R.S.; K, A.; C H, C.; K, N.; Kar, D. Bioengineering Microbes for Improved Nutritional Value and Health Benefits.. Preprints 2023, 2023050057. https://doi.org/10.20944/preprints202305.0057.v1 Pandya, J.; Adiga, R.S.; K, A.; C H, C.; K, N.; Kar, D. Bioengineering Microbes for Improved Nutritional Value and Health Benefits.. Preprints 2023, 2023050057. https://doi.org/10.20944/preprints202305.0057.v1

Abstract

Microbe bioengineering has the potential to improve the nutritional value and health benefits of food products. Modifying microbial cells to produce specific proteins or compounds that can improve human health is one approach. Penicillin and recombinant insulin are two examples of this. The production of recombinant insulin by genetically modified E. coli bacteria has transformed diabetes treatment by providing a consistent and cost-effective source of insulin. Previously, insulin was extracted from the pancreas of animals, which was an expensive process that frequently resulted in impurities that could cause adverse reactions. Bioengineered insulin is now the standard diabetes treatment, providing a safe and effective method of controlling blood glucose levels. Bacteria, for example, can be genetically modified to produce vitamins like B12, which are difficult to obtain from plant sources. Likewise, yeasts can be genetically modified to produce β-carotene, a precursor to vitamin A that is required for vision, immune function, and skin health. Overall, bioengineered microorganisms have the potential to provide significant health benefits by producing essential compounds and proteins. Because of ongoing advances in genetic engineering techniques and understanding microbial metabolism, the possibilities for improving human health through bioengineering are limitless.

Keywords

bioengineered; recombinant; E. coli; insulin; penicillin; cancer; vitamin B12; replacement therapy; nutrition; mABs

Subject

Biology and Life Sciences, Biology and Biotechnology

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