Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Radiotherapy in Uveal Melanoma: A Review of Ocular Complications

Lamprini Banou
ORCID logo ,
Zoi Tsani
ORCID logo ,
Konstantinos Arvanitogiannis
,
Maria Pavlaki
,
Anna Dastiridou
ORCID logo ,
Sofia Androudi
* ORCID logo
Version 1 : Received: 1 May 2023 / Approved: 2 May 2023 / Online: 2 May 2023 (03:03:31 CEST)

A peer-reviewed article of this Preprint also exists.

Banou, L.; Tsani, Z.; Arvanitogiannis, K.; Pavlaki, M.; Dastiridou, A.; Androudi, S. Radiotherapy in Uveal Melanoma: A Review of Ocular Complications. Curr. Oncol. 2023, 30, 6374-6396. Banou, L.; Tsani, Z.; Arvanitogiannis, K.; Pavlaki, M.; Dastiridou, A.; Androudi, S. Radiotherapy in Uveal Melanoma: A Review of Ocular Complications. Curr. Oncol. 2023, 30, 6374-6396.

Abstract

Uveal melanoma represents the most prevalent form of primary malignant intraocular tumor in adults. Historically, enucleation was considered the gold-standard approach in the treatment of uveal melanoma. Nowadays, radiotherapy is the most commonly used therapy, aiming at a better quality of life. However, radiotherapy can result in several ocular complications, some of which may be vision-threatening. Radiation-induced dry eye, scleral necrosis, cataract, rubeosis iridis, neovascular glaucoma, radiation retinopathy and maculopathy and optic neuropathy are the most common. This article aims to summarize the current literature on the ocular complications after radiotherapy, their clinical features, risk factors and management strategies. A thorough understanding is crucial for ophthalmologists and oncologists to provide optimal patient care, improve visual outcomes, and minimize long-term complications.

Keywords

uveal melanoma; radiotherapy; ocular complications

Subject

Medicine and Pharmacology, Ophthalmology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.