Version 1
: Received: 6 March 2023 / Approved: 7 March 2023 / Online: 7 March 2023 (09:24:17 CET)
How to cite:
Busby, C. Childhood Leukemia Increased Significantly in Wales and Scotland After Chernobyl: A Biological Explanation. Preprints2023, 2023030130. https://doi.org/10.20944/preprints202303.0130.v1
Busby, C. Childhood Leukemia Increased Significantly in Wales and Scotland After Chernobyl: A Biological Explanation. Preprints 2023, 2023030130. https://doi.org/10.20944/preprints202303.0130.v1
Busby, C. Childhood Leukemia Increased Significantly in Wales and Scotland After Chernobyl: A Biological Explanation. Preprints2023, 2023030130. https://doi.org/10.20944/preprints202303.0130.v1
APA Style
Busby, C. (2023). Childhood Leukemia Increased Significantly in Wales and Scotland After Chernobyl: A Biological Explanation. Preprints. https://doi.org/10.20944/preprints202303.0130.v1
Chicago/Turabian Style
Busby, C. 2023 "Childhood Leukemia Increased Significantly in Wales and Scotland After Chernobyl: A Biological Explanation" Preprints. https://doi.org/10.20944/preprints202303.0130.v1
Abstract
Employing data supplied by the Oxford-based UK Childhood Cancer Research Group in 2003 it is shown that after the Chernobyl accident, childhood leukemia by single age and year of birth in the 0-4y cohort increased significantly in Wales and Scotland combined in the period 1986-1990 compared with controls born 1970-1985 and 1991-1994. Relative risk RR = 1.41; 95% CI 1.20<RR<1.65; p = 0.00004. These exposure periods were chosen because whole body Caesium-137 monitoring had demonstrated that internal exposures persisted for more than 4 years. The dose-response exhibits saturation and reversal, interpreted as biological censoring effects in the developing individual.
Keywords
Leukemias; Risk and prevention; Epidemiology and outreach; Chernobyl; Radiation
Subject
Environmental and Earth Sciences, Environmental Science
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.