Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Myocarditis and Pericarditis Following the SARS-CoV-2 Infection and COVID-19 Vaccination

Version 1 : Received: 4 February 2023 / Approved: 6 February 2023 / Online: 6 February 2023 (07:51:04 CET)

How to cite: Mohseni Afshar, Z.; Liang, J.; Habib, M.A.; Taghizadeh Moghadam, M.A.; Babazadeh, A.; Ramzani, E.; Hosseinzadeh, R.; Hashemi, E.; Sio, T.T.; Allahgholipour, A.; Barary, M.; Ebrahimpour, S. Myocarditis and Pericarditis Following the SARS-CoV-2 Infection and COVID-19 Vaccination. Preprints 2023, 2023020085. https://doi.org/10.20944/preprints202302.0085.v1 Mohseni Afshar, Z.; Liang, J.; Habib, M.A.; Taghizadeh Moghadam, M.A.; Babazadeh, A.; Ramzani, E.; Hosseinzadeh, R.; Hashemi, E.; Sio, T.T.; Allahgholipour, A.; Barary, M.; Ebrahimpour, S. Myocarditis and Pericarditis Following the SARS-CoV-2 Infection and COVID-19 Vaccination. Preprints 2023, 2023020085. https://doi.org/10.20944/preprints202302.0085.v1

Abstract

Cardiac complications of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been well-identified since the beginning of the current coronavirus disease 2019 (COVID-19) pandemic. Such conditions can occur of various etiologies, such as respiratory failure and hypoxemia, direct cardiac tissue damage due to viral replication, indirect myocarditis as systemic inflammation, and the interaction of different medications. Recently, with the start of the COVID-19 vaccination programs, COVID-19 vaccine-associated cardiac adverse events (AEs) have emerged and are increasingly being reported. Although these AEs are usually mild and self-limited, they can sometimes cause severe, catastrophic outcomes. This review compares the pathophysiology, diagnosis, and treatment of the de novo SARS-CoV-2 infection-related and COVID-19 vaccine-related myocarditis and pericarditis.

Keywords

SARS-CoV-2; COVID-19; Vaccines; Myocarditis; Pericarditis

Subject

Medicine and Pharmacology, Epidemiology and Infectious Diseases

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