Version 1
: Received: 22 January 2023 / Approved: 26 January 2023 / Online: 26 January 2023 (02:58:19 CET)
How to cite:
Pinheiro, C.S.D.M.; De Carvalho Neta, A.V.; Pinheiro Neto, V.F.; Oliveira, C.Q.D.R.; Ribeiro, R.M.; Borges, A.C.R.; Borges, M.O.D.R. Plant-based Bone Grafting: The Future of Bone Healing. Preprints2023, 2023010462. https://doi.org/10.20944/preprints202301.0462.v1
Pinheiro, C.S.D.M.; De Carvalho Neta, A.V.; Pinheiro Neto, V.F.; Oliveira, C.Q.D.R.; Ribeiro, R.M.; Borges, A.C.R.; Borges, M.O.D.R. Plant-based Bone Grafting: The Future of Bone Healing. Preprints 2023, 2023010462. https://doi.org/10.20944/preprints202301.0462.v1
Pinheiro, C.S.D.M.; De Carvalho Neta, A.V.; Pinheiro Neto, V.F.; Oliveira, C.Q.D.R.; Ribeiro, R.M.; Borges, A.C.R.; Borges, M.O.D.R. Plant-based Bone Grafting: The Future of Bone Healing. Preprints2023, 2023010462. https://doi.org/10.20944/preprints202301.0462.v1
APA Style
Pinheiro, C.S.D.M., De Carvalho Neta, A.V., Pinheiro Neto, V.F., Oliveira, C.Q.D.R., Ribeiro, R.M., Borges, A.C.R., & Borges, M.O.D.R. (2023). Plant-based Bone Grafting: The Future of Bone Healing. Preprints. https://doi.org/10.20944/preprints202301.0462.v1
Chicago/Turabian Style
Pinheiro, C.S.D.M., Antônio Carlos Romão Borges and Marilene Oliveira da Rocha Borges. 2023 "Plant-based Bone Grafting: The Future of Bone Healing" Preprints. https://doi.org/10.20944/preprints202301.0462.v1
Abstract
Objectives Bone fractures are very common diseases, which can be caused by impact injuries or physiological disorders. Thus, the present review aimed to study the use of medicinal plants in the healing mechanism of bone fractures. Evidence acquisition Through research in the PubMed, Google Academic, and Scielo databases, this article reviews 11 ethnopharmacological studies and 34 preclinical studies on the biological actions of different plants in bone fracture healing mechanism. Results Indian tribes have highlighted in the plants ethnopharmacological study for various diseases, including bone fractures. However, despite the large citations of traditional use, technical-scientific studies are still scarce in the literature. Chenopodium ambrosioides, Piper sarmentosum, quadrangular Cissus, Ricinus communis and Radix salvia miltiorrhiza plants were the most studied in the literature regarding their osteogenic, angiogenic, anti-inflammatory and remodeling effects, acting on bone receptors, stimulating bone metabolism, increasing minerals uptake, and assisting in free radicals breakdown. Conclusion Thus, the medicinal plants use is promising in the field of bone regeneration, as well as being alternative when conventional therapies are unfeasible, increasing herbal medicines demand and popularity.
Keywords
Bone healing; , bone fracture; bone graft; herbal medicine; osteogenesis; plants
Subject
Medicine and Pharmacology, Veterinary Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
,
,
,
