Version 1
: Received: 17 January 2023 / Approved: 18 January 2023 / Online: 18 January 2023 (10:22:43 CET)
How to cite:
Fofanova, E. Serotonin Impact on Lifespan Longevity in Marine Annelid D.gyrociliatus. Preprints2023, 2023010334. https://doi.org/10.20944/preprints202301.0334.v1
Fofanova, E. Serotonin Impact on Lifespan Longevity in Marine Annelid D.gyrociliatus. Preprints 2023, 2023010334. https://doi.org/10.20944/preprints202301.0334.v1
Fofanova, E. Serotonin Impact on Lifespan Longevity in Marine Annelid D.gyrociliatus. Preprints2023, 2023010334. https://doi.org/10.20944/preprints202301.0334.v1
APA Style
Fofanova, E. (2023). Serotonin Impact on Lifespan Longevity in Marine Annelid D.gyrociliatus. Preprints. https://doi.org/10.20944/preprints202301.0334.v1
Chicago/Turabian Style
Fofanova, E. 2023 "Serotonin Impact on Lifespan Longevity in Marine Annelid D.gyrociliatus" Preprints. https://doi.org/10.20944/preprints202301.0334.v1
Abstract
Serotonin (5-HT) is crucial molecule in animal kingdom. It is involved in control of multiple processes. It might act via transmembrane receptors or via postranslational protein modification (serotonylation). D. gyrociliatus is a marine worm-like invertebrate with quite short lifespan. In this study lifetime experiments were performed. We incubated freshly laid eggs, adult females lifelong in HTP, PCPA and cystamine. Every week we monitored the survived individuals. This was lifelong (about 5 moth) monitoring. The survival analysis demonstrated that PCPA and cystamine reduce lifespan longevity drastically and even in F1 offsprings from mothers with reduced level of serotonin. HTP incubation to the contary extended mean lifespan longevity up to 22 % even in F1 offsprings from mothers with extended levels of serotonin. Thus, our results demonstrated that serotonin impacts lifespan longevity and moreover the level of serotonin in mother organism affects offspring lifespan longevity.
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
