Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Ovarian Pregnancy: A Systematic Review and 2 Case Reports

Version 1 : Received: 23 December 2022 / Approved: 28 December 2022 / Online: 28 December 2022 (01:16:33 CET)

A peer-reviewed article of this Preprint also exists.

Almahloul, Z.; Amro, B.; Nagshabandi, Z.; Alkiumi, I.; Hakim, Z.; Wattiez, A.; Tahlak, M.; Koninckx, P.R. Ovarian Pregnancy: 2 Case Reports and a Systematic Review. J. Clin. Med. 2023, 12, 1138. Almahloul, Z.; Amro, B.; Nagshabandi, Z.; Alkiumi, I.; Hakim, Z.; Wattiez, A.; Tahlak, M.; Koninckx, P.R. Ovarian Pregnancy: 2 Case Reports and a Systematic Review. J. Clin. Med. 2023, 12, 1138.

Abstract

Objective Ovarian pregnancy is a rare but well-known pathology. However, pathophysiology, diagnosis and treatment are not clearly established. Data sources. All case reports published in Pubmed from Nov 2011 till Nov 2022. Study eligibility criteria. A systematic review and 2 case reports of ovarian pregnancy Study appraisal and synthesis methods. Not applicable Results Ovarian pregnancies occur in 8% of women without or blocked oviducts and in 23% on the other side than the corpus luteum and the symptoms of ovarian pregnancies are not specific. Therefore ovarian pregnancy has to be suspected in all women with abdominal bleeding. As for extrauterine pregnancies, the presence of an intrauterine pregnancy does not rule out an ovarian pregnancy. Surgical excision is the preferred treatment. Important is that in women with both an intra-uterine and an ovarian pregnancy, care should be taken not to damage the corpus luteum. Conclusions Ovarian pregnancies can occur in women with blocked tubes, on the other side of the corpus luteum, in the presence of an intrauterine pregnancy, and even when pregnancy tests or tranvaginal ultrasonography are negative. The diagnosis being difficult to exclude, a laparoscopy is indicated in all women with intra-abdominal bleeding, keeping in mind that an intra-uterine pregnancy cannot be exluded and that a corpus luteum need to be respected.

Keywords

ectopic pregnancy; heterotopic pregnancy; laparoscopy; methotrexate; corpus luteum

Subject

Biology and Life Sciences, Cell and Developmental Biology

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.