Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

An Isotonic Drink containing Pacific cod (Gadus macrocephalus) Processing Waste Collagen Hydrolysate for Prevention of Bone and Cartilage Disorders

Nikita Yu. Zarubin
ORCID logo ,
Elena N. Kharenko
,
Olga V. Bredikhina
,
Elizaveta V. Lavrukhina
,
Konstantin V. Zolotarev
* ORCID logo ,
Anton N. Mikhailov
,
Valeriya I. Nakhod
,
Marina V. Mikhailova
Version 1 : Received: 9 December 2022 / Approved: 13 December 2022 / Online: 13 December 2022 (09:40:37 CET)

How to cite: Zarubin, N.Y.; Kharenko, E.N.; Bredikhina, O.V.; Lavrukhina, E.V.; Zolotarev, K.V.; Mikhailov, A.N.; Nakhod, V.I.; Mikhailova, M.V. An Isotonic Drink containing Pacific cod (Gadus macrocephalus) Processing Waste Collagen Hydrolysate for Prevention of Bone and Cartilage Disorders. Preprints 2022, 2022120235. https://doi.org/10.20944/preprints202212.0235.v1 Zarubin, N.Y.; Kharenko, E.N.; Bredikhina, O.V.; Lavrukhina, E.V.; Zolotarev, K.V.; Mikhailov, A.N.; Nakhod, V.I.; Mikhailova, M.V. An Isotonic Drink containing Pacific cod (Gadus macrocephalus) Processing Waste Collagen Hydrolysate for Prevention of Bone and Cartilage Disorders. Preprints 2022, 2022120235. https://doi.org/10.20944/preprints202212.0235.v1

Abstract

Malnutrition is one of major factors of bone and cartilage disorders. Pacific cod (Gadus macrocephalus) processing waste is a cheap and highly promising source of bioactive substances, including collagen-derived peptides and amino acids, for bone and cartilage structure stabilization. Addition of these substances to a functional drink is one of the ways to achieve their fast intestinal absorption. Collagen hydrolysate was obtained via enzymatic hydrolysis, ultrafiltration, freeze-drying, and grinding to powder. The lyophilized hydrolysate was a light gray powder with high protein content (>90%), including collagen (about 85% of total protein) and a complete set of essential and non-essential amino acids. The hydrolysate was applicable as a protein food supply or a structure-forming food component due to presence of collagen fiber fragments. An isotonic fitness drink (osmolality 298.1 ± 2.1 mOsm/L) containing the hydrolysate and vitamin C as a cofactor in collagen biosynthesis was prepared. Addition of the hydrolysate did not adversely affect its organoleptic parameters. Production of such functional foods and drinks is one of the beneficial ways of fish processing waste utilization.

Keywords

bone and cartilage disorders; bioactive substances; Pacific cod; processing waste utilization; collagen hydrolysate; isotonic drink.

Subject

Engineering, Industrial and Manufacturing Engineering

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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