Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Epizootic Haemorrhagic Disease Virus Serotype 8 in Tunisia, 2021

Version 1 : Received: 9 November 2022 / Approved: 10 November 2022 / Online: 10 November 2022 (09:59:16 CET)

A peer-reviewed article of this Preprint also exists.

Sghaier, S.; Sailleau, C.; Marcacci, M.; Thabet, S.; Curini, V.; Ben Hassine, T.; Teodori, L.; Portanti, O.; Hammami, S.; Jurisic, L.; Spedicato, M.; Postic, L.; Gazani, I.; Ben Osman, R.; Zientara, S.; Bréard, E.; Calistri, P.; Richt, J.A.; Holmes, E.C.; Savini, G.; Di Giallonardo, F.; Lorusso, A. Epizootic Haemorrhagic Disease Virus Serotype 8 in Tunisia, 2021. Viruses 2023, 15, 16. Sghaier, S.; Sailleau, C.; Marcacci, M.; Thabet, S.; Curini, V.; Ben Hassine, T.; Teodori, L.; Portanti, O.; Hammami, S.; Jurisic, L.; Spedicato, M.; Postic, L.; Gazani, I.; Ben Osman, R.; Zientara, S.; Bréard, E.; Calistri, P.; Richt, J.A.; Holmes, E.C.; Savini, G.; Di Giallonardo, F.; Lorusso, A. Epizootic Haemorrhagic Disease Virus Serotype 8 in Tunisia, 2021. Viruses 2023, 15, 16.

Abstract

Epizootic haemorrhagic disease (EHD) is a Culicoides-borne viral disease caused by epizootic haemorrhagic disease virus (EHDV) and associated with clinical manifestations in cervids and bovids. In late September 2021, EHDV was reported in cattle farms in central/western Tunisia. It rapidly spread throughout the country with more than 200 confirmed outbreaks. A combination of classical and molecular techniques was applied to characterize the causative virus as a member of EHDV-8 serotype. This is the first evidence of EHDV- 8 circulation since 1982 when the prototype EHDV-8 strain was isolated in Australia. This work highlights the urgent need for vaccines for a range of EHDV serotypes.

Keywords

EHDV; Tunisia; virus characterization; EHDV serotype 8; circulation

Subject

Medicine and Pharmacology, Veterinary Medicine

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