Preprint Article Version 2 Preserved in Portico This version is not peer-reviewed

Mapping the Accessory Proteins (Orfs) of Severe Acute Respiratory Syndrome Coronavirus 2

Version 1 : Received: 7 October 2022 / Approved: 11 October 2022 / Online: 11 October 2022 (16:15:57 CEST)
Version 2 : Received: 2 November 2022 / Approved: 3 November 2022 / Online: 3 November 2022 (10:27:01 CET)

A peer-reviewed article of this Preprint also exists.

Thomas, S. Mapping the Accessory Proteins (Orfs) of Severe Acute Respiratory Syndrome Coronavirus 2. Re:GEN Open 2023, 3, 1–10, doi:10.1089/regen.2022.0056. Thomas, S. Mapping the Accessory Proteins (Orfs) of Severe Acute Respiratory Syndrome Coronavirus 2. Re:GEN Open 2023, 3, 1–10, doi:10.1089/regen.2022.0056.

Abstract

The COVID-19 pandemic first observed in December 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has influenced every individual on the planet. The virus has influenced our lifestyle, education, economy and the environment. Though the vaccines against COVID-19 have provided protection against the disease; new strains of the virus have lowered the efficiency of the vaccines. There is still no effective therapy for the treatment of the disease. Understanding the protein structure of the virus may lead to the development of effective therapies for the disease. We recently mapped the structural proteins and non-structural proteins of SARS-CoV-2. The accessory proteins (Open reading frames, Orfs) of SARS-CoV-2 modulate the host environment to favor virus replication. This paper reports mapping the accessory proteins (Orfs) of SARS-CoV-2.

Keywords

severe acute respiratory syndrome coronavirus 2; SARS-CoV-2; COVID-19; accessory protein; mapping; structure; Open reading frame, Orf.

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

Comments (1)

Comment 1
Received: 3 November 2022
Commenter: Sunil Thomas
Commenter's Conflict of Interests: Author
Comment: Included new figures
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