Version 1
: Received: 29 September 2022 / Approved: 30 September 2022 / Online: 30 September 2022 (11:19:07 CEST)
How to cite:
Song, X.; Ma, M.; Wang, Y.; Chen, L.; Yu, J.; Yin, H.; Shang, Q. In Vitro Fermentation of Carrot Juice by the Human Gut Microbiota: Potential Use of It as A Novel Prebiotic Agent. Preprints2022, 2022090488. https://doi.org/10.20944/preprints202209.0488.v1
Song, X.; Ma, M.; Wang, Y.; Chen, L.; Yu, J.; Yin, H.; Shang, Q. In Vitro Fermentation of Carrot Juice by the Human Gut Microbiota: Potential Use of It as A Novel Prebiotic Agent. Preprints 2022, 2022090488. https://doi.org/10.20944/preprints202209.0488.v1
Song, X.; Ma, M.; Wang, Y.; Chen, L.; Yu, J.; Yin, H.; Shang, Q. In Vitro Fermentation of Carrot Juice by the Human Gut Microbiota: Potential Use of It as A Novel Prebiotic Agent. Preprints2022, 2022090488. https://doi.org/10.20944/preprints202209.0488.v1
APA Style
Song, X., Ma, M., Wang, Y., Chen, L., Yu, J., Yin, H., & Shang, Q. (2022). <em>In Vitro</em> Fermentation of Carrot Juice by the Human Gut Microbiota: Potential Use of It as A Novel Prebiotic Agent. Preprints. https://doi.org/10.20944/preprints202209.0488.v1
Chicago/Turabian Style
Song, X., Hua Yin and Qingsen Shang. 2022 "<em>In Vitro</em> Fermentation of Carrot Juice by the Human Gut Microbiota: Potential Use of It as A Novel Prebiotic Agent" Preprints. https://doi.org/10.20944/preprints202209.0488.v1
Abstract
Carrot juice and its associated beverage products are well-known healthy drinks all over the world. However, what effect carrot juice has on the human gut microbiota and how it is fermented by the intestinal microbes have not been studied. Here, using an in vitro model of anaerobic fermentation, we demonstrated that carrot juice could be fermented into lactate and acetate by the human gut microbiota. 16S high-throughput sequencing and bioinformatic analyses indicated that fermentation of carrot juice could significantly change the composition of the human gut microbiome. Interestingly, carrot juice remarkably increased the abundances of beneficial bacteria, including Lactobacillus fermentum, Lactobacillus salivarius, Lactobacillus mucosae and Bacteroides uniformis and decreased the population of opportunistic pathogenic bacteria, such as Enterococcus faecium in the gut. Collectively, our study illustrates a favorable effect of carrot juice on the human gut microbiota and lays a foundation for the development of carrot juice as a novel prebiotic agent.
Keywords
carrot juice; human gut microbiota; fermentation; prebiotic; lactate; Lactobacillus fermentum; Lactobacillus salivarius; Lactobacillus mucosae; Bacteroides uniformis; Enterococcus faecium
Subject
Biology and Life Sciences, Food Science and Technology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
