Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Elemental Laser-Plasma Analysis of Pointed Gourd Leaves for Diabetes Management

Version 1 : Received: 22 September 2022 / Approved: 22 September 2022 / Online: 22 September 2022 (09:41:00 CEST)

How to cite: Kumar, T.; Rai, P.K.; Rai, A.K.; Rai, N.K.; Rai, A.K.; Parigger, C.; Watal, G.; Yadav, S. Elemental Laser-Plasma Analysis of Pointed Gourd Leaves for Diabetes Management. Preprints 2022, 2022090337 (doi: 10.20944/preprints202209.0337.v1). Kumar, T.; Rai, P.K.; Rai, A.K.; Rai, N.K.; Rai, A.K.; Parigger, C.; Watal, G.; Yadav, S. Elemental Laser-Plasma Analysis of Pointed Gourd Leaves for Diabetes Management. Preprints 2022, 2022090337 (doi: 10.20944/preprints202209.0337.v1).

Abstract

This interdisciplinary work communicates identification and quantification of elements responsible for the bioactive potency of leaves from pointed gourd, trichosanthes dioica,using laser induced breakdown spectroscopy (LIBS). Calibration-free LIBS determines the presence of various trace and major elements, their concentrations, and ratios in which they are present in the leaves. The presence of specific elemental ratios of magnesium/sodium and magnesium/potassium could be promising for managing diabetes mellitus. Variable doses of 500, 750, 1000, and 1250 mg per kg body weight of aqueous extract from trichosanthes dioica leaves are administered. A dose of 1000 mg per kg body weight is found to be the most effective. Based on encouraging results, the extract could be harvested to serve as anti-diabetic medication for diabetes and associated symptoms.

Keywords

optical emission spectroscopy; laser induced optical breakdown; trichosanthes dioica; pointed gourd; diabetes; biomedicine; biophysics

Subject

PHYSICAL SCIENCES, Applied Physics

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