Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

A Systematic Review and Quality Evaluation of Studies on Long-Term Sequelae of COVID-19

Version 1 : Received: 14 September 2022 / Approved: 14 September 2022 / Online: 14 September 2022 (08:50:08 CEST)

How to cite: Vásconez González, J.; Izquiero-Condoy, J.S.; Fernandez-Naranjo, R.; Ortiz-Prado, E. A Systematic Review and Quality Evaluation of Studies on Long-Term Sequelae of COVID-19. Preprints 2022, 2022090200 (doi: 10.20944/preprints202209.0200.v1). Vásconez González, J.; Izquiero-Condoy, J.S.; Fernandez-Naranjo, R.; Ortiz-Prado, E. A Systematic Review and Quality Evaluation of Studies on Long-Term Sequelae of COVID-19. Preprints 2022, 2022090200 (doi: 10.20944/preprints202209.0200.v1).

Abstract

Background: COVID-19 made its debut as a pandemic in 2020; since then, more than 607 million cases and at least 6.5 million deaths have been reported worldwide. While the burden of disease has been described, the long-term effects or chronic sequelae are still being described. Objective: To describe the findings of a current systematic review of the long-term effects related to post-COVID-19 sequelae. Design: A systematic review was carried out in which cohort studies, case series, clinical case reports were included, and the PubMed, Scielo, SCOPUS and Web of Science databases were ex-tracted. Information published 2020 to June 1, 2022, was sought. Results: We reviewed 300 manuscripts during the first step of the literature review process. Then 260 abstracts were analyzed. In the end, we included 32 manuscripts: 9 for pulmonary, 6 for cardiac, 2 for renal, 9 for neurological and psychiatric, and 8 for cutaneous sequelae. Conclusion: Studies show that the most common sequelae are those linked to the lungs, followed by skin, cutaneous and psychiatric alterations. Women report a higher incidence of the sequelae, as well as those with comorbidities and severer COVID-19 history. The COVID-19 pandemic has not only caused death and disease since its apparition but has also sickened millions of people around the globe who potentially suffer from serious illnesses that will continue to add to the list of health problems and further burden healthcare systems around the world.

Keywords

sequelae; COVID-19; SARS-COV-2; long-COVID; systematic review

Subject

MEDICINE & PHARMACOLOGY, General Medical Research

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.

We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.