Review
Version 1
Preserved in Portico This version is not peer-reviewed
Tissue Engineering in Gynecology
Version 1
: Received: 8 September 2022 / Approved: 9 September 2022 / Online: 9 September 2022 (07:33:27 CEST)
A peer-reviewed article of this Preprint also exists.
Brownell, D.; Chabaud, S.; Bolduc, S. Tissue Engineering in Gynecology. Int. J. Mol. Sci. 2022, 23, 12319. Brownell, D.; Chabaud, S.; Bolduc, S. Tissue Engineering in Gynecology. Int. J. Mol. Sci. 2022, 23, 12319.
Abstract
Female gynecological organ dysfunction can cause infertility and psychological distress, decreasing quality of life of affected women. Incidence is constantly increasing due to growing rates of cancer and delaying of childbearing age in the developed world. Current treatments are often unable to restore organ function, and occasionally are the cause for female infertility. Alternative treatment options are currently being developed in order to face the inadequacy of current practices. In this review, pathologies and current treatments of gynecological organs (ovaries, uterus, and vagina) will be described. The state-of-the-art of tissue engineering alternatives to common practices are evaluated with a focus on in vivo models. Tissue engineering is an ever-expanding field, integrating various domains of modern science to create sophisticated tissue substitutes in the hopes of repairing or replacing dysfunctional organs using autologous cells. Application to gynecology has the potential of restoring female fertility and sexual wellbeing.
Keywords
tissue engineering; ovary; uterus; vagina; gynecology
Subject
Medicine and Pharmacology, Obstetrics and Gynaecology
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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