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Isolation and Characterization of Staphylococcus Phage Rih21 and Evaluation of its Antibacterial Activity against Methicillin-resistant Staphylococcus aureus Clinical Isolates

Submitted:

30 August 2022

Posted:

01 September 2022

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Abstract
From the hospital waste-water, a novel bacteriophage was isolated and characterized. According to characterization properties, this bacteriophage belongs to the Siphoviridae family, the maximum bacteriophage titer was recorded at 37°C and a pH of 7.2, had a 44,789 bp linear double-strand DNA genome, and within the genome sequence, there are 61 genes, all of which are encoded into proteins. Although this bacteriophage does not have any virulence factors or antimicrobial resistance genes and had specific lytic activity against some antimicrobial resistance S. aureus clinical isolates.
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