Chalán-Gualán, S.; Castro, V.; Oropeza, R.; Suárez, M.; Albericio, F.; Rodríguez, H. 3,4-Dihydro-2(1H)-Pyridones as Building Blocks of Synthetic Relevance. Molecules2022, 27, 5070.
Chalán-Gualán, S.; Castro, V.; Oropeza, R.; Suárez, M.; Albericio, F.; Rodríguez, H. 3,4-Dihydro-2(1H)-Pyridones as Building Blocks of Synthetic Relevance. Molecules 2022, 27, 5070.
Chalán-Gualán, S.; Castro, V.; Oropeza, R.; Suárez, M.; Albericio, F.; Rodríguez, H. 3,4-Dihydro-2(1H)-Pyridones as Building Blocks of Synthetic Relevance. Molecules2022, 27, 5070.
Chalán-Gualán, S.; Castro, V.; Oropeza, R.; Suárez, M.; Albericio, F.; Rodríguez, H. 3,4-Dihydro-2(1H)-Pyridones as Building Blocks of Synthetic Relevance. Molecules 2022, 27, 5070.
Abstract
3,4-Dihydro-2(1H)-pyridones (3,4-DHPo) and their derivatives are privileged structures present in natural products, which has been increased its relevance due to its biological activity in front of a broad range of targets, but especially for its importance as synthetic precursors of a variety of compounds with marked biological activity. Taking into account the large number of contributions published over the years regarding this kind of heterocycle, here we presented a current view of 3,4-dihydro-2(1H)-pyridones (3,4-DHPo), which include general aspects such as those related to nomenclature, synthesis, and biological activity; but also highlighting the importance of DHPo as building blocks of other relevance structures.
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