Preprint Communication Version 1 This version is not peer-reviewed

The Adapted Autonomic Profile (Aap) Home-Based Test for the Evaluation of Neuro-Cardiovascular Autonomic Dysfunction

Version 1 : Received: 22 June 2022 / Approved: 23 June 2022 / Online: 23 June 2022 (10:56:27 CEST)
Version 2 : Received: 23 June 2022 / Approved: 24 June 2022 / Online: 24 June 2022 (04:23:06 CEST)

How to cite: Sivan, M.; Corrado, J.; Mathias, C. The Adapted Autonomic Profile (Aap) Home-Based Test for the Evaluation of Neuro-Cardiovascular Autonomic Dysfunction . Preprints 2022, 2022060325 (doi: 10.20944/preprints202206.0325.v1). Sivan, M.; Corrado, J.; Mathias, C. The Adapted Autonomic Profile (Aap) Home-Based Test for the Evaluation of Neuro-Cardiovascular Autonomic Dysfunction . Preprints 2022, 2022060325 (doi: 10.20944/preprints202206.0325.v1).

Abstract

Autonomic dysfunction is an increasingly recognised complication in chronic neurological conditions such as Parkinson’s disease , and other medical conditions, including diabetes mellitus, chronic fatigue syndrome, fibromyalgia and recently Long Covid. Despite laboratory-based tests to evaluate normal and abnormal autonomic function, there are no home-based tests to record neuro-cardiovascular autonomic responses to common stimuli in daily life that are dependent on the normal functioning of the autonomic nervous system. We have developed an adapted blood pressure/heart Autonomic Profile (aAP) that can be used by an individual independently and repeatedly in a domiciliary setting to determine the physiological and symptomatic response to standing, food, and physical and mental (cognitive, emotional) activities. The aAP aids separating autonomic failure (often irreversible) from autonomic dysfunction. This helps the individual understand the relationship between symptoms and common triggers in daily life, and informs on self-management in debilitating conditions such as postural tachycardia syndrome (PoTS) and Long Covid.

Keywords

autonomic failure; lean test; active stand; long covid; Post-COVID-19 condition

Subject

MEDICINE & PHARMACOLOGY, Cardiology

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