Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Association between Mortality and Cardiovascular Diseases in Vulnerable Mexican Populations, A Retrospective Study of the COVID-19 Pandemic

Version 1 : Received: 12 June 2022 / Approved: 14 June 2022 / Online: 14 June 2022 (03:11:35 CEST)

A peer-reviewed article of this Preprint also exists.

Padilla-Rivas, G.R.; Delgado-Gallegos, J.L.; Garza-Treviño, G.; Galan-Huerta, K.A.; G-Buentello, Z.; Roacho-Pérez, J.A.; Santoyo-Suarez, M.G.; Franco-Villareal, H.; Leyva-Lopez, A.; Estrada-Rodriguez, A.E.; et al. Association between Mortality and Cardiovascular Diseases in the Vulnerable Mexican Population: A Cross-Sectional Retrospective Study of the COVID-19 Pandemic. Frontiers in Public Health 2022, 10, doi:10.3389/fpubh.2022.1008565. Padilla-Rivas, G.R.; Delgado-Gallegos, J.L.; Garza-Treviño, G.; Galan-Huerta, K.A.; G-Buentello, Z.; Roacho-Pérez, J.A.; Santoyo-Suarez, M.G.; Franco-Villareal, H.; Leyva-Lopez, A.; Estrada-Rodriguez, A.E.; et al. Association between Mortality and Cardiovascular Diseases in the Vulnerable Mexican Population: A Cross-Sectional Retrospective Study of the COVID-19 Pandemic. Frontiers in Public Health 2022, 10, doi:10.3389/fpubh.2022.1008565.

Abstract

Cardiovascular diseases (CVD´s) continue as the primary cause of death worldwide. During the past couple of years, and with the surge of the COVID-19 pandemic, deaths linked to CVD´s were -slightly overshadowed by those deaths related to COVID-19, albeit during the highest peaks of the pandemic. The present study derived form understanding the correlation between both diseases, from the standpoint of patients already diagnosed with CVD´s (n = 41883) and what comorbidities had the highest influence on overall patient death (n = 3637). Obesity, hypertension, and diabetes are all linked to worsening the outcome of COVID-19 positive patients, hence they were considered when looking at the overview of all CVD positive patients. Our finding showed that 1697 deaths were related to diabetes (p < 0.001), 987 deaths were related to obesity (p < 0.001), and lastly 2499 deaths were attributed to hypertension (p < 0.001) individually. Using logistic regression modeling, we found diabetes (OR: 1.744, p < 0.001) and hypertension (OR: 2.179, p < 0.001) had a high impact on patient deaths. Hence, having a CVD diagnosis, with hypertension and/or diabetes seems to increase the likely-hood of complication leading to death in COVID-19 positive patients.

Keywords

cardiovascular diseases; Mexico COVID-19; Mexico metropolitan area

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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