Sailike, B.; Jin, W.; Askarova, S.; Adilbayeva, A.; Jenis, J.; Akbay, B.; Omarova, Z.; Tokay, T. Neuroprotective and Anti-Epileptic Potentials of Genus Artemisia L.. Preprints2022, 2022050293. https://doi.org/10.20944/preprints202205.0293.v1
APA Style
Sailike, B., Jin, W., Askarova, S., Adilbayeva, A., Jenis, J., Akbay, B., Omarova, Z., & Tokay, T. (2022). Neuroprotective and Anti-Epileptic Potentials of Genus Artemisia L.. Preprints. https://doi.org/10.20944/preprints202205.0293.v1
Chicago/Turabian Style
Sailike, B., Zhannur Omarova and Tursonjan Tokay. 2022 "Neuroprotective and Anti-Epileptic Potentials of Genus Artemisia L." Preprints. https://doi.org/10.20944/preprints202205.0293.v1
Abstract
Epilepsy is a chronic neuronal disorder characterized by periodic, unpredictable, and recurrent seizures due to either a genetically determined or an acquired brain disorder. Although many anti-epileptics drugs (AEDs) are developed to control epilepsy, 30% of patients still need additional drugs or experience recurrent seizures and psychiatric and behavioral side effects. Thus, the need for medical care for patients with uncontrolled epilepsy remains unmet. The Genus Artemisia L. is one of the largest genera in the Asteraceae family with more than 500 species widely distributed in Europe, Asia, and North America. Many Artemisia species have been used in various treatments since ancient times as folk remedies. They demonstrated strong antioxidant, anti-inflammatory, antimicrobial, antimalarial, and antitumor activity. Recent studies reveal that some species of Artemisia demonstrated a therapeutic benefit for epilepsy by its anti-oxidant, anti-inflammatory, neuroprotective, and anticonvulsant properties. In this review, we investigate the current state of the literature regarding the neuroprotective and antiepileptic potentials of the genus Artemisia and its possible underlying mechanisms.
Keywords
Genus Artemisia; anticonvulsant; antioxidant; antiapoptosis; anti-neuroinflammatory; neuropro-tective; cognitive function
Subject
Biology and Life Sciences, Anatomy and Physiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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