Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Identifying Hotspots of Peoples Diagnosed with Tuberculosis and Drug Addiction of Alcohol, Tobacco and other Drugs through a Geospatial Intelligence Application on Communities from Southern Brazil

Version 1 : Received: 31 March 2022 / Approved: 4 April 2022 / Online: 4 April 2022 (07:22:45 CEST)

A peer-reviewed article of this Preprint also exists.

Scholze, A.R.; Delpino, F.M.; Alves, L.S.; Alves, J.D.; Berra, T.Z.; Ramos, A.C.V.; Fuentealba-Torres, M.; Fronteira, I.; Arcêncio, R.A. Identifying Hotspots of People Diagnosed of Tuberculosis with Addiction to Alcohol, Tobacco, and Other Drugs through a Geospatial Intelligence Application in Communities from Southern Brazil. Trop. Med. Infect. Dis. 2022, 7, 82. Scholze, A.R.; Delpino, F.M.; Alves, L.S.; Alves, J.D.; Berra, T.Z.; Ramos, A.C.V.; Fuentealba-Torres, M.; Fronteira, I.; Arcêncio, R.A. Identifying Hotspots of People Diagnosed of Tuberculosis with Addiction to Alcohol, Tobacco, and Other Drugs through a Geospatial Intelligence Application in Communities from Southern Brazil. Trop. Med. Infect. Dis. 2022, 7, 82.

Abstract

(1) Background: tuberculosis (TB) is considered one of the leading causes of death by a single in-fectious agent worldwide. This study aimed to identify hotspots of people diagnosed with tu-berculosis and abusive use of alcohol, tobacco and other drugs in communities through a geo-spatial intelligence application; (2) Methods: ecological study with a spatio-temporal approach. We considered tuberculosis cases diagnosed and registered in the Notifiable Diseases Information System, which presented information on alcoholism, smoking, and other drugs. Spatial Variations in Temporal Trends (SVTT) and scan statistics were applied for the identification of Hotspots; (3) Results: of 29.499 cases of tuberculosis were identified. And when we applied the STTT for al-coholism, three Hotspots were detected, one of which was protective (RR: 0.08 – CI95%: 0.02 – 0.32) and two at risk (RR:1.42 – CI95%: 1.11 – 1.73; RR: 1.39 - CI95%: 1.28 – 1.50). Regarding smoking, two risk clusters were identified (RR: 1.15 - CI95%: 1.01 – 1.30; RR: 1.68 - CI95%: 1.54 – 1.83). For other drugs, a risk cluster was found (RR: 1.13 - CI95%: 0.99 – 1.29) and two protections (RR: 0.70 - CI95%: 0.63 – 0.77; RR: 0.76 – CI95%: 0.65 – 0.89); (4) Conclusions: it was evidenced in the communities a problem of TB and drug addiction. Use disorder perhaps in a person's brain and behavior and leads to an inability to continue their treatment, putting the community at risk for TB.

Keywords

Tuberculosis; Alcoholism; Illicit drugs; Tobacco use disorder; Spatial analysis

Subject

Biology and Life Sciences, Virology

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