Version 1
: Received: 26 March 2022 / Approved: 28 March 2022 / Online: 28 March 2022 (14:30:09 CEST)
How to cite:
Gildea, L.; Ayariga, J.; Ajayi, O.; Xu, J.; Villafane, R.; Samuel-Foo, M. Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against S. typhimurium and S. newington. Preprints2022, 2022030367. https://doi.org/10.20944/preprints202203.0367.v1.
Gildea, L.; Ayariga, J.; Ajayi, O.; Xu, J.; Villafane, R.; Samuel-Foo, M. Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against S. typhimurium and S. newington. Preprints 2022, 2022030367. https://doi.org/10.20944/preprints202203.0367.v1.
Cite as:
Gildea, L.; Ayariga, J.; Ajayi, O.; Xu, J.; Villafane, R.; Samuel-Foo, M. Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against S. typhimurium and S. newington. Preprints2022, 2022030367. https://doi.org/10.20944/preprints202203.0367.v1.
Gildea, L.; Ayariga, J.; Ajayi, O.; Xu, J.; Villafane, R.; Samuel-Foo, M. Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against S. typhimurium and S. newington. Preprints 2022, 2022030367. https://doi.org/10.20944/preprints202203.0367.v1.
Abstract
Products derived from Cannabis sativa have gained increased interest and popularity. As these products become common amongst the public, the heath and potential therapeutic values associated with hemp have become a premier focus of research. While the psychoactive and medicinal properties of Cannabis products have been extensively highlighted in literature, the antibacterial properties of CBD have not been explored in depth. This research serves to examine the antibacterial potential of CBD against Salmonella newington and Salmonella typhimurium. In this study we observed bacterial response to CBD exposure through biological assays, bacterial kinetics, and fluorescence microscopy. Additionally, comparative studies between CBD and ampicillin were conducted against Salmonella typhimurium and Salmonella newington to determine comparative efficacy. Furthermore, we observed potential resistance development of our Salmonella spp. against CBD treatment.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
