Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Roles of Carbonic Anhydrases and Carbonic Anhydrases Related Proteins in Zebrafish

Version 1 : Received: 25 March 2022 / Approved: 25 March 2022 / Online: 25 March 2022 (09:22:10 CET)

How to cite: Aspatwar, A.; Syrjänen, L.; Parkkila, S. Roles of Carbonic Anhydrases and Carbonic Anhydrases Related Proteins in Zebrafish. Preprints 2022, 2022030344. https://doi.org/10.20944/preprints202203.0344.v1 Aspatwar, A.; Syrjänen, L.; Parkkila, S. Roles of Carbonic Anhydrases and Carbonic Anhydrases Related Proteins in Zebrafish. Preprints 2022, 2022030344. https://doi.org/10.20944/preprints202203.0344.v1

Abstract

During the last decades, zebrafish (Danio rerio) has become one of the most important model organisms to study different physiological and biological phenomena. Research field of carbonic anhydrases (CAs) and carbonic anhydrase related proteins (CARPs) is not an exception in this. The best-known known function of CAs is the regulation of acid-base balance. However, studies performed with zebrafish, among others, have revealed important roles for these proteins in many other physiological processes, some of which have been unpredicted in the light of the previous studies and suggestions. Examples are roles in zebrafish pigmentation as well as motor coordination. Disruption of the function of these proteins may generate even lethal outcomes. In this review, we summarize the current knowledge of CA-related studies performed in zebrafish.

Keywords

carbonic anhydrase; carbonic anhydrase related proteins; acid-base balance; ion transport; pH regulation; motor coordination; zebrafish

Subject

Biology and Life Sciences, Biochemistry and Molecular Biology

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