Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Outpatient High-Dose-Rate Mold Brachytherapy for Lower Gingival Squamous Cell Carcinoma: A First Report

Ami Takeshita
,
Hiroaki Shimamoto
* ORCID logo ,
Yuka Uchimoto
,
Tomomi Tsujimoto
,
Tetsuo Miyamoto
,
Sven Kreiborg
,
Sanjay M Mallya
,
Michio Oda
,
Takero Hirata
,
Kazuhiko Ogawa
,
Hiroya Shiomi
,
Shumei Murakami
Version 1 : Received: 28 February 2022 / Approved: 1 March 2022 / Online: 1 March 2022 (12:44:09 CET)

How to cite: Takeshita, A.; Shimamoto, H.; Uchimoto, Y.; Tsujimoto, T.; Miyamoto, T.; Kreiborg, S.; Mallya, S.M.; Oda, M.; Hirata, T.; Ogawa, K.; Shiomi, H.; Murakami, S. Outpatient High-Dose-Rate Mold Brachytherapy for Lower Gingival Squamous Cell Carcinoma: A First Report. Preprints 2022, 2022030022. https://doi.org/10.20944/preprints202203.0022.v1 Takeshita, A.; Shimamoto, H.; Uchimoto, Y.; Tsujimoto, T.; Miyamoto, T.; Kreiborg, S.; Mallya, S.M.; Oda, M.; Hirata, T.; Ogawa, K.; Shiomi, H.; Murakami, S. Outpatient High-Dose-Rate Mold Brachytherapy for Lower Gingival Squamous Cell Carcinoma: A First Report. Preprints 2022, 2022030022. https://doi.org/10.20944/preprints202203.0022.v1

Abstract

Brachytherapy is often applied to oral cancers, with good outcomes and minimal loss of oral function. Especially, mold brachytherapy is best suited for superficial oral cancers with little or no bone invasion, such as gingival cancer, palatal mucosal cancer, or buccal mucosal cancer because of the thin tissue thickness that needs to be irradiated. A few cases have been reported on mold brachytherapy for gingival cancers, especially with high-dose-rates (HDR), these treatments were performed during hospitalization. We report a case of lower gingival squamous cell carcinoma (SCC) treated with HDR mold brachytherapy in an outpatient setting. A 71-year-old male with lower gingival SCC had received HDR mold brachytherapy (54 Gy, 9 fractions, 5 days) as an outpatient. Eighteen months after the mold therapy, the patient had no recurrence and no metastasis. A search of the literature revealed no previous report of a case of gingival cancer treated with HDR mold brachytherapy in an outpatient.

Keywords

gingival cancer; mold brachytherapy; radiation therapy; outpatient

Subject

Biology and Life Sciences, Toxicology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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