Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Recent Advances of Natural Cellulosic Non-Woven Scaffolds for Tissue Engineering

Version 1 : Received: 14 February 2022 / Approved: 14 February 2022 / Online: 14 February 2022 (14:02:16 CET)

A peer-reviewed article of this Preprint also exists.

Aghazadeh, M.R.; Delfanian, S.; Aghakhani, P.; Homaeigohar, S.; Alipour, A.; Shahsavarani, H. Recent Advances in Development of Natural Cellulosic Non-Woven Scaffolds for Tissue Engineering. Polymers 2022, 14, 1531. Aghazadeh, M.R.; Delfanian, S.; Aghakhani, P.; Homaeigohar, S.; Alipour, A.; Shahsavarani, H. Recent Advances in Development of Natural Cellulosic Non-Woven Scaffolds for Tissue Engineering. Polymers 2022, 14, 1531.

Journal reference: Polymers 2022, 14, 1531
DOI: 10.3390/polym14081531

Abstract

In the recent years, tissue engineering researchers have exploited a variety of biomaterials that can potentially mimic extracellular matrix (ECM) for tissue regeneration. Natural cellulose, mainly obtained from bacterial (BC) and plant-based (PC) sources, can serve as a high potential scaffold material for different regenerative purposes. Natural cellulose has drawn the attention of researchers due to its advantage over synthetic cellulose in terms of availability, cost-effectiveness, perfusablility, biocompatibility, negligible toxicity, mild immune response and due to imitating native tissues. In this article, we will review the recent in vivo and in vitro studies aimed to assess the potentials of natural cellulose for the purpose of soft (skin, heart, veins, nerve, among others) and hard (bone and tooth) tissue engineering.

Keywords

Polymeric Biomaterials; Natural Cellulose; Tissue Engineering; Differentiation; Bone Regeneration; Skin Regeneration; Cardiac Regeneration; Vascular Regeneration; Neural Regeneration

Subject

MEDICINE & PHARMACOLOGY, Other

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