Nardi, M.; Bonacci, S.; Herrera Cano, N.; Oliverio, M.; Procopio, A. The Highly Efficient Synthesis of 1,2-Disubstituted Benzimidazoles Using Microwave Irradiation. Molecules2022, 27, 1751.
Nardi, M.; Bonacci, S.; Herrera Cano, N.; Oliverio, M.; Procopio, A. The Highly Efficient Synthesis of 1,2-Disubstituted Benzimidazoles Using Microwave Irradiation. Molecules 2022, 27, 1751.
Nardi, M.; Bonacci, S.; Herrera Cano, N.; Oliverio, M.; Procopio, A. The Highly Efficient Synthesis of 1,2-Disubstituted Benzimidazoles Using Microwave Irradiation. Molecules2022, 27, 1751.
Nardi, M.; Bonacci, S.; Herrera Cano, N.; Oliverio, M.; Procopio, A. The Highly Efficient Synthesis of 1,2-Disubstituted Benzimidazoles Using Microwave Irradiation. Molecules 2022, 27, 1751.
Abstract
A microwave assisted method for synthesis of 2-substituted benzimidazoles has been developed. The combination of molar ratio N-phenyl-o-phenylenediamine:benzaldehyde (1:1) using microwave irradiation and only 1% mol of Er(OTf)3 provide an efficient, environmental and mild access to a diversity of benzimidazoles under solvent-free conditions.
Keywords
microwave; green chemistry; benzimidazoles
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright:
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