Aphicho, K.; Kittipanukul, N.; Uttamapinant, C. Visualizing the Complexity of Proteins in Living Cells with Genetic Code Expansion. Current Opinion in Chemical Biology 2022, 66, 102108, doi:10.1016/j.cbpa.2021.102108.
Aphicho, K.; Kittipanukul, N.; Uttamapinant, C. Visualizing the Complexity of Proteins in Living Cells with Genetic Code Expansion. Current Opinion in Chemical Biology 2022, 66, 102108, doi:10.1016/j.cbpa.2021.102108.
Aphicho, K.; Kittipanukul, N.; Uttamapinant, C. Visualizing the Complexity of Proteins in Living Cells with Genetic Code Expansion. Current Opinion in Chemical Biology 2022, 66, 102108, doi:10.1016/j.cbpa.2021.102108.
Aphicho, K.; Kittipanukul, N.; Uttamapinant, C. Visualizing the Complexity of Proteins in Living Cells with Genetic Code Expansion. Current Opinion in Chemical Biology 2022, 66, 102108, doi:10.1016/j.cbpa.2021.102108.
Abstract
Genetic code expansion has emerged as an enabling tool to provide insight into functions of understudied proteinogenic species such as small proteins and peptides, and to probe protein biophysics in the cellular context. Here we discuss recent technical advances and applications of genetic code expansion in cellular imaging of complex mammalian protein species, along with considerations and challenges upon using the method.
Biology and Life Sciences, Biochemistry and Molecular Biology
Copyright:
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