Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series

Version 1 : Received: 25 November 2021 / Approved: 29 November 2021 / Online: 29 November 2021 (07:48:13 CET)

How to cite: De Rose, C.; Miceli Sopo, S.; Valentini, P.; Morello, R.; Biasucci, D.; Buonsenso, D. Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series. Preprints 2021, 2021110513 (doi: 10.20944/preprints202111.0513.v1). De Rose, C.; Miceli Sopo, S.; Valentini, P.; Morello, R.; Biasucci, D.; Buonsenso, D. Potential Application of Lung Ultrasound in Children with Severe Uncontrolled Asthma: Preliminary Hypothesis Based on a Case Series. Preprints 2021, 2021110513 (doi: 10.20944/preprints202111.0513.v1).

Abstract

In recent years, lung ultrasound (LUS) has been increasingly used for the diagnosis of respiratory diseases in both adult and pediatric patients. However, asthma is a field in which the use of LUS is not yet well defined or is in development. In the following case series, we describe clinical, laboratory, radiological results as well as detailed lung ultrasound findings of 6 children with asthma: some of them with acute asthma attack and with inadequately controlled allergic asthma or childhood asthma; others with acute asthma and allergic or infantile asthma adequately controlled by preventive therapy. Finally we describe the clinical, laboratory and imaging parameters of a child with severe allergic asthma in the absence of exacerbation. In these cases, albeit at different times, LUS played an important role in both the initial diagnostic process and follow-up. It also showed different ultrasound features depending on the severity of the individual asthma based on the type of asthmatic phenotype and control of it.

Keywords

lung ultrasound; LUS, children; asthma; personalized medicine

Subject

MEDICINE & PHARMACOLOGY, Pediatrics

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