Preprint Communication Version 2 Preserved in Portico This version is not peer-reviewed

The Case for Standardising Gene Nomenclature Across Vertebrates

Version 1 : Received: 27 September 2021 / Approved: 29 September 2021 / Online: 29 September 2021 (10:25:19 CEST)
Version 2 : Received: 27 April 2022 / Approved: 29 April 2022 / Online: 29 April 2022 (08:09:45 CEST)

How to cite: McCarthy, F.M.; Jones, T.E.; Kwitek, A.E.; Smith, C.L.; Vize, P.D.; Westerfield, M.; Bruford, E.A. The Case for Standardising Gene Nomenclature Across Vertebrates. Preprints 2021, 2021090485 (doi: 10.20944/preprints202109.0485.v2). McCarthy, F.M.; Jones, T.E.; Kwitek, A.E.; Smith, C.L.; Vize, P.D.; Westerfield, M.; Bruford, E.A. The Case for Standardising Gene Nomenclature Across Vertebrates. Preprints 2021, 2021090485 (doi: 10.20944/preprints202109.0485.v2).

Abstract

Standardized gene nomenclature supports unambiguous communication and identification of the scientific literature associated with genes. To support the increasing number of annotated genomes that are now available for comparative studies, gene nomenclature authorities coordinate the assignment of approved gene names that can be readily propagated across species. Theofanopoulou et al. (Theofanopoulou et al. 2021) propose a new nomenclature for the genes encoding oxytocin and arginine vasopressin and their receptors. Rather than changing to a different nomenclature system, we propose minor updates to the current approved nomenclature of these vertebrate genes to better reflect their evolutionary history. We call on authors, journal editors and reviewers to help support communication and indexing of gene-related publications by working with existing gene nomenclature committees and ensuring that standardized gene nomenclature is routinely used.

Keywords

gene nomenclature; vertebrate genomics; oxytocin; arginine vasopressin

Subject

LIFE SCIENCES, Genetics

Comments (1)

Comment 1
Received: 29 April 2022
Commenter: Tamsin Jones
Commenter's Conflict of Interests: Author
Comment: We have significantly revised this manuscript to focus more on the larger issues raised about gene nomenclature changes, and moved detailed discussion of the specific nomenclature of the oxytocin and arginine vasopressin ligand and receptor genes to the Supplementary Information. We have also added to the Supplement more details about the procedures followed by the gene nomenclature committees.
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