Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Systematic Review and Meta-Analysis of the Use of Hyaluronic Acid Injections to Restore Interproximal Papillae

Version 1 : Received: 26 September 2021 / Approved: 28 September 2021 / Online: 28 September 2021 (11:08:28 CEST)

How to cite: Sanchez-Perez, A.; Rosa-Vela, T.; Mateos-Moreno, B.; Jornet-Garcia, A.; Navarro-Cuellar, C. Systematic Review and Meta-Analysis of the Use of Hyaluronic Acid Injections to Restore Interproximal Papillae. Preprints 2021, 2021090464 (doi: 10.20944/preprints202109.0464.v1). Sanchez-Perez, A.; Rosa-Vela, T.; Mateos-Moreno, B.; Jornet-Garcia, A.; Navarro-Cuellar, C. Systematic Review and Meta-Analysis of the Use of Hyaluronic Acid Injections to Restore Interproximal Papillae. Preprints 2021, 2021090464 (doi: 10.20944/preprints202109.0464.v1).

Abstract

The absence of interdental papillae leads to the appearance of black triangle. For most patients, the appearance of these triangles is an important reason for concern and affects their social relationships. Multiple reconstruction techniques have been developed with different degrees of success and predictability. The main aim of this study was to evaluate the efficiency of hyaluronic acid (HA) injected into interproximal papillae six months after injection and to perform a systematic review and meta-analysis. After a systematic review, five articles were selected: a clinical randomised controlled trial and four clinical trials. In total, eighty-five patients with a deficiency in upper papillae in the front of the maxilla and jaw were included in the study. The height variable was evaluated (mm) six months after HA injection. In total, one hundred and four interproximal papillae were studied. Three articles showed an important difference in favour of intervention. The total result regarding in the injection of AH was favourable with an approximate average filling of 0.7 mm in the height of the interdental papilla. The injection of HA for the reconstruction of deficient papillae in the region of the upper and lower maxilla was a possible option treatment strategy.

Keywords

aesthetics; gingiva; hyaluronic acid; injections; surgical procedures; minimally invasive

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