Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Review of Pharmacological Properties of Channa Striatus (Haruan) In Diabetes and Cardiovascular Complications

Version 1 : Received: 8 August 2021 / Approved: 9 August 2021 / Online: 9 August 2021 (14:59:08 CEST)

How to cite: Azemi, A.K.; Mustapha, S.; Mohammed, M.; Rasool, A.H.G.; Ishak, R.; Mat Jais, A.M.; Mokhtar, S.S. Review of Pharmacological Properties of Channa Striatus (Haruan) In Diabetes and Cardiovascular Complications. Preprints 2021, 2021080200 (doi: 10.20944/preprints202108.0200.v1). Azemi, A.K.; Mustapha, S.; Mohammed, M.; Rasool, A.H.G.; Ishak, R.; Mat Jais, A.M.; Mokhtar, S.S. Review of Pharmacological Properties of Channa Striatus (Haruan) In Diabetes and Cardiovascular Complications. Preprints 2021, 2021080200 (doi: 10.20944/preprints202108.0200.v1).

Abstract

Diabetes mellitus remains a major risk factor for developing cardiovascular diseases, resulting in increased morbidity and mortality associated with cardiovascular complications. Given the burden of diabetes-related cardiovascular complications, there is a need to identify strategies, safe and effective therapeutic agents that could effectively prevent and control diabetes. Presently, many patients living with diabetes depends on traditional medicines as an alternative cure. Channa striatus (Haruan) is a freshwater fish traditionally used to treat wounds, inflammations, and pains. Several pharmacological investigations have supported the folkloric claims of C. striatus extracts, including hypoglycemic, hypolipidemic, antioxidant, anti-inflammatory, and pro-platelet aggregation activities. The therapeutic potentials of C. striatus were demonstrated to be associated with the presence of high content essential amino acids and good fatty acids known to improve cell growth and facilitate wound healing. Therefore, C. striatus bioactive compounds have great potentials to serve as lead candidates in developing novel therapeutic agents for the management of diabetes and related cardiovascular diseases. This review aims to provide a comprehensive overview of the pharmacological properties and therapeutic potentials of C. striatus for the management of diabetes and associated cardiovascular complications.

Keywords

antioxidant; anti-inflammatory; cardiovascular; Channa striatus; diabetes

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