Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Factors Influencing Physician Decision Making to Attempt Advanced Resuscitation in Asystolic Out-of-Hospital Cardiac Arrest

Version 1 : Received: 17 July 2021 / Approved: 20 July 2021 / Online: 20 July 2021 (11:48:59 CEST)

How to cite: Payot, C.; Fehlmann, C.A.; Suppan, L.; Niquille, M.; Lardi, C.; Sarasin, F.P.; Larribau, R. Factors Influencing Physician Decision Making to Attempt Advanced Resuscitation in Asystolic Out-of-Hospital Cardiac Arrest. Preprints 2021, 2021070447 (doi: 10.20944/preprints202107.0447.v1). Payot, C.; Fehlmann, C.A.; Suppan, L.; Niquille, M.; Lardi, C.; Sarasin, F.P.; Larribau, R. Factors Influencing Physician Decision Making to Attempt Advanced Resuscitation in Asystolic Out-of-Hospital Cardiac Arrest. Preprints 2021, 2021070447 (doi: 10.20944/preprints202107.0447.v1).

Abstract

The objective of this study was to identify the key elements used by prehospital emergency physicians (EP) to decide whether or not to attempt advanced life support (ALS) in asystolic out-of-hospital cardiac arrest (OHCA). From 01.01.2009 to 01.01.2017, all adult victims of asystolic OHCA in Geneva, Switzerland, were retrospectively included. Patients with signs of "obvious death" or with a Do-Not-Attempt-Resuscitation order were excluded. Patients were categorized as having received ALS if this was mentioned in the medical record, or, failing that, if at least one dose of adrenaline had been administered during cardio-pulmonary resuscitation (CPR). Prognostic factors known at the time of EP's decision were included in a multivariable logistic regression model. 784 patients were included. Factors favourably influencing the decision to provide ALS were witnessed OHCA (OR=2.14, 95%CI1.43–3.20) and bystander CPR (OR=4.10, 95%CI2.28–7.39). Traumatic aetiology (OR=0.04, 95%CI0.02–0.08), age >80 years (OR=0.14, 95%CI0.09–0.24) and a Charlson comorbidity index greater than 5 (OR=0.12, 95%CI0.06–0.27) were the factors most strongly associated with the decision not to attempt ALS. Factors influencing the EP’s decision to attempt ALS in asystolic OHCA are the relatively young age of the patients, few comorbidities, presumed medical aetiology, witnessed OHCA and bystander CPR.

Keywords

out-of-hospital cardiac arrest; emergency physician; medical decision; asystole; advanced life support; Charlson comorbidity index; emergency medical service; prehospital emergency

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